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Biological and Medicinal Chemistry

Working Paper

Hypoxia-Activated Small Molecule-Induced Gene Expression

Sarah L. Collins, Jaideep Saha, Laure C. Bouchez, Ester M. Hammond, Stuart Conway

Version 1 posted 24 July 2018

727

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Organic Chemistry

Working Paper

Signal-triggered release of allyl-caged tertiary amine drugs from polymer hydrogels

Rienk Eelkema, Benjamin Klemm, Magherita Tavasso, Irene Piergentili, Max Satijn, Tobias Breve, Pouyan Boukany

Version 1 posted 31 January 2024

592

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1

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Biological and Medicinal Chemistry

Working Paper

Nitroreductase-Mediated Release of Inhibitors of Lysine-Specific Demethylase 1 (LSD1) from Prodrugs in Transfected Acute Myeloid Leukaemia Cells

Manfred Jung, Eva-Maria Herrlinger, Mirjam Hau, Desiree M. Redhaber, Gabriele Greve, Dominica Willmann, Simon Steimle, Michael Müller, Michael Lübbert, Cornelius Miething, Roland Schüle

Version 1 posted 24 October 2019

969

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Catalysis

Working Paper

Mild Organic Base-Catalyzed Primary Alcohol-Selective Aroylation Reaction Using N-Aroylcarbazoles for Underexplored Prodrugs

Yasuaki Morita, Bubwoong Kang, Rubi Nakashima, Yuki Shimizu, Asumi Sakai, Maiko Moriguchi, Yoko Yasuno, Tetsuya Satoh, Tetsuro Shinada, Masaki Kuse

Version 1 posted 09 June 2020

730

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Biological and Medicinal Chemistry

Working Paper

Click Activated Protodrugs Against Cancer Increase the Therapeutic Potential of Chemotherapy through Local Capture and Activation

Kui Wu, Nathan Yee, Sangeetha Srinivasan, Amir Mahmoodi, Michael Zakharian, Jose M. Mejia Oneto, Maksim Royzen

Version 2 posted 02 November 2020

2,673

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Biological and Medicinal Chemistry

Working Paper

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

Anna Skwarska, Ewen Calder, Deborah Sneddon, Hannah Bolland, Maria Odyniec, Ishna N. Mistry, Jennifer Martin, Lisa Folkes, Ester M. Hammond, Stuart Conway

Version 2 posted 23 March 2021

1,142

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Inorganic Chemistry

Working Paper

Direct Measurement of the Visible to UV Photodissociation Processes for the PhotoCORM TryptoCORM

Rosaria Cercola, Kaitlyn Fischer, Summer Scherman, etienne garand, Natalie Wong, Anders Hammarback, Jason Lynam, Ian Fairlamb, Caroline E. H. Dessent

Version 1 posted 23 December 2019

423

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Organic Chemistry

Working Paper

Desymmetrization of Pibrentasvir for Efficient Prodrug Synthesis

Eric Voight, Stephen Greszler, John Hartung, Jianguo Ji, Russell C. Klix, John T. Randolph, Bhadra Shelat, Jan E. Waters, David A. DeGoey

Version 1 posted 28 April 2021

315

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Biological and Medicinal Chemistry

Working Paper

Tetrazine-Triggered Bioorthogonal Cleavage of trans-Cyclooctene-Caged Phenols Using a Minimal Self-Immolative Linker Strategy

Patrick Keppel, Barbara Sohr, Walter Kuba, Philipp Skrinjar, Jonathan Carlson, Hannes Mikula

Version 1 posted 23 June 2022

542

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Biological and Medicinal Chemistry

Working Paper

HSA-hijacking nanobinders built on bioresponsive prodrugs for combined cancer chemoimmunotherapy

Matilde Tubertini, Luca Menilli, Celeste Milani, Cecilia Martini, Maria Luisa Navacchia, Marta Nugnes, Manuela Bartolini, Marina Naldi, Daniele Tedesco, Elisa Martella, Andrea Guerrini, Claudia Ferroni, Francesca Moret, Greta Varchi

Version 1 posted 24 August 2023

138

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1

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Refine Search

12 results in prodrugs in Keywords: prodrugs

Hypoxia-Activated Small Molecule-Induced Gene Expression

Signal-triggered release of allyl-caged tertiary amine drugs from polymer hydrogels

Nitroreductase-Mediated Release of Inhibitors of Lysine-Specific Demethylase 1 (LSD1) from Prodrugs in Transfected Acute Myeloid Leukaemia Cells

Mild Organic Base-Catalyzed Primary Alcohol-Selective Aroylation Reaction Using N-Aroylcarbazoles for Underexplored Prodrugs

Click Activated Protodrugs Against Cancer Increase the Therapeutic Potential of Chemotherapy through Local Capture and Activation

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

Direct Measurement of the Visible to UV Photodissociation Processes for the PhotoCORM TryptoCORM

Desymmetrization of Pibrentasvir for Efficient Prodrug Synthesis

Tetrazine-Triggered Bioorthogonal Cleavage of trans-Cyclooctene-Caged Phenols Using a Minimal Self-Immolative Linker Strategy

HSA-hijacking nanobinders built on bioresponsive prodrugs for combined cancer chemoimmunotherapy

12 results in Keywords: prodrugs