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Biological and Medicinal Chemistry

Working Paper

Optimization of binding affinities in chemical space with generative pretrained transformer and deep reinforcement learning

Xiaopeng Xu, Juexiao Zhou, Chen Zhu, Qing Zhan, Zhongxiao Li, Ruochi Zhang, Yu Wang, Xingyu Liao, Xin Gao

Version 1 posted 03 April 2023

370

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Organic Chemistry

Working Paper

Regiodivergent Functionalization of Protected and Unprotected Carbohydrates via an Adaptive Activating Strategy

Shen Cao, Haobo Zhang, Mingshuo Chen, Niming Zhu, Beibei Zhan, Peng Xu, Xiaoping Chen, Biao Yu, Xiaheng Zhang

Version 1 posted 02 July 2024

422

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Catalysis

Working Paper

Direct and Modular Access to Allylic Amines via Nickel-Catalyzed Three-Component Coupling

Changyu Xu, Jianchao Chang, Zhan Dong, Liangliang Song, Liang-An Chen

Version 1 posted 28 July 2023

330

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Materials Science

Working Paper

Impurity Conundrum of Organic Room Temperature Afterglow

Chengjian Chen, Zhenguo Chi, Kok Chan Chong, Andrei S. Batsanov, Zhan Yang, Zhu Mao, Zhiyong Yang, Bin Liu

Version 1 posted 27 September 2019

2,674

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3

Citations

Nanoscience

Working Paper

The glycerol stabilized calcium phosphate cluster for rapid remineralization of tooth enamel by a water-triggered transformation

Bing-Qiang Lu, Xi Chen, Feng Chen, Nan Luo, Yu-Wei Deng, Hua Zeng, Yu Zhang, Jing-Yu Zhan, Xiao-Chen Xu, Gui-Zhi Cao, Jin Wen, Zhiyuan Zhang, Xi-Ping Feng, Xinquan Jiang

Version 1 posted 05 June 2023

349

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Polymer Science

Working Paper

Enabling Tunable Hydrophilicity of PDMS via Metal-ligand Coordinated Dynamic Networks

Xinyue Zhang, Ralph Crisci, John. A Finlay, Hongyi Cai, Anthony S. Clare, Zhan Chen, Meredith N. Silberstein

Version 1 posted 16 November 2021

328

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Catalysis

Working Paper

A General and Modular Access to Enantioenriched α Trifluoromethyl Ketones via Nickel-Catalyzed Reductive Cross-Coupling

Liang-An Chen, Dengkai Lin, Yongzhi Chen, Zhan Dong, Pan Pei, Haiting Ji, Lanzhu Tai

Version 1 posted 15 March 2022

674

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1

Citations

Biological and Medicinal Chemistry

Working Paper

Synthesis, antiproliferative activity, and biological profiling of C-19 trityl and silyl ether andrographolide analogs in colon cancer and breast cancer cells

Tiffany Gu, Rushika Raval, Zachary Bashkin, Carina Zhou, Sanghyuk Ko, Natalie Kong, Seoyeon Hong, Aditya Bhaskara, Samarth Shah, Aditi Joshi, Samahith Thellakal, Kaitlyn Rim, Anushree Marimuthu, Srishti Venkatesan, Emma Wang, Sophia Li, Aditi Jayabalan, Alice Tao, Yilin Fang, Lorelei Xia, Aidan Chui, Emily Shu, Tracy Zhang, Zhan Chen, Edward Njoo

Version 1 posted 16 October 2024

250

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Refine Search

8 results in Zhan Chen in Authors: Zhan Chen

Optimization of binding affinities in chemical space with generative pretrained transformer and deep reinforcement learning

Regiodivergent Functionalization of Protected and Unprotected Carbohydrates via an Adaptive Activating Strategy

Direct and Modular Access to Allylic Amines via Nickel-Catalyzed Three-Component Coupling

Impurity Conundrum of Organic Room Temperature Afterglow

The glycerol stabilized calcium phosphate cluster for rapid remineralization of tooth enamel by a water-triggered transformation

Enabling Tunable Hydrophilicity of PDMS via Metal-ligand Coordinated Dynamic Networks

A General and Modular Access to Enantioenriched α Trifluoromethyl Ketones via Nickel-Catalyzed Reductive Cross-Coupling

Synthesis, antiproliferative activity, and biological profiling of C-19 trityl and silyl ether andrographolide analogs in colon cancer and breast cancer cells

8 results in Authors: Zhan Chen