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Biological and Medicinal Chemistry

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thiamine diphosphate

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5 results in Keywords: thiamine diphosphate

Biological and Medicinal Chemistry

Evaluation of Ketoclomazone and its Analogues as Inhibitors of Thiamine Diphosphate (ThDP)-dependent Enzymes

Alex H. Y. Chan, Terence C. S. Ho, Imam Fathoni, Rawia Hamid, Anna K. H. Hirsch, Kevin J. Saliba, Finian James Leeper

Version 1 posted 17 January 2024

147

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Biological and Medicinal Chemistry

Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes by Triazole-based Thiamine Analogues

Alex H. Y. Chan, Terence C. S. Ho, Imam Fathoni, Rebecca Pope, Kevin J. Saliba, Finian James Leeper

Version 1 posted 25 January 2023

184

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Biological and Medicinal Chemistry

Open-chain thiamine analogues as potent inhibitors of thiamine pyrophosphate (TPP)-dependent enzymes

Alex H. Y. Chan, Terence C. S. Ho, Finian James Leeper

Version 1 posted 30 May 2023

106

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Biological and Medicinal Chemistry

Strategies on Designing Thiamine Analogues for Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes: Systematic Investigation through Scaffold Switching and C2-Functionalisation

Alex H. Y. Chan, Terence C. S. Ho, Rimsha Irfan, Rawia A. A. Hamid, Emma S. Rudge, Amjid Iqbal, Alex Turner, Anna K. H. Hirsch, Finian James Leeper

Version 2 posted 20 February 2023

246

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Biological and Medicinal Chemistry

Triazole-Based Thiamine Analogues as Inhibitors of Thiamine Pyrophosphate-Dependent Enzymes: 1,3-Dicarboxylate for Metal Binding

Terence C. S. Ho, Alex H. Y. Chan, Finian James Leeper

Version 1 posted 09 May 2024

115

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