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Physical Chemistry

Working Paper

The Properties of α-Synuclein Secondary Nuclei are Dominated by the Solution Conditions Rather than the Seed Fibril Strain

Alessia Peduzzo, Sara Linse, Alexander Buell

Version 1 posted 04 September 2019

847

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1

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Biological and Medicinal Chemistry

Working Paper

An Anthrone-Based Kv7.2/7.3 Channel Blocker with Improved Properties for the Investigation of Psychiatric and Neurodegenerative Disorders

Jacob Porter, Oscar Vivas-Rodriguez, C. David Weaver, Eamonn Dickson, Abdulmohsen Alsafran, Elliot DiMilo, Leggy Arnold, Chris Dockendorff

Version 1 posted 10 June 2019

563

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Biological and Medicinal Chemistry

Working Paper

Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable and Blood Brain Barrier Penetrant Prote-olysis Targeting Chimera Degrader of Leucine Rich Repeat Kinase 2

Xingui Liu, Alexia Kalogeropulou, Sofia Domingos, Nikolai Makukhin, Raja Nirujogi, Francois Singh, Natalia Shpiro, Anton Saalfrank, Esther Sammler, Ian Ganley, Rui Moreira, Dario Alessi, Alessio Ciulli

Version 2 posted 13 July 2022

4,472

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1

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Biological and Medicinal Chemistry

Working Paper

Discovery and characterization of benzyloxy piperidine based dopamine 4 receptor antagonists

Kirsten Tolentino, Viktoriya Mashinson, Anish Vadukoot, Corey Hopkins

Version 1 posted 22 September 2021

249

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Analytical Chemistry

Working Paper

TD GC-MS and UPLC-MS methods to discover differentially expressed metabolites in sebum

Thomas D. Hoare, Caitlin Walton-Doyle, Katherine A. Hollywood, Eleanor Sinclair, Drupad K. Trivedi, Perdita Barran

Version 1 posted 13 December 2023

275

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Analytical Chemistry

Working Paper

Cyclic Ion Mobility-Mass Spectrometry and Tandem Collision Induced Unfolding for Quantification of Elusive Protein Biomarkers

Devin Makey, Varun Gadkari, Robert Kennedy, Brandon Ruotolo

Version 1 posted 25 January 2024

418

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Analytical Chemistry

Working Paper

Rapid Electrochemical Detection of Levodopa using Polyaniline-Modified Screen-Printed Electrodes for the Improved Management of Parkinson's Disease

Henrique Noguchi, Sarbjeet Kaur, Luiza Krettli, Pankaj Singla, Jake McClements, Helena Snyder, Robert Crapnell, Craig Banks, Katarina Novakovic, Inderpreet Kaur, Jonas Gruber, James Dawson, Marloes Peeters

Version 1 posted 18 August 2022

295

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Biological and Medicinal Chemistry

Working Paper

Inhibition of Ubiquitin Phosphorylation by Nucleoside Analogues

Olivia A Lambourne, Shane Bell, Lea P Wilhelm, Erika B Yarbrough, Gabriel G Holly, Oliver M Russell, Arwa Alghamdi, Azeza M Fdel, Carmine Varricchio, Emma L Lane, Ian G Ganley, Arwyn T Jones, Matthew S Goldberg, Youcef Mehellou

Version 1 posted 22 December 2022

363

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1

Citations

Analytical Chemistry

Working Paper

Interpretable machine learning on metabolomics data reveals biomarkers for Parkinson’s disease

J. Diana Zhang, Chonghua Xue, Vijaya B. Kolachalama, William A. Donald

Version 1 posted 08 December 2022

428

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Biological and Medicinal Chemistry

Working Paper

Assessing Vesicular Monoamine Transport and Toxicity Using Fluorescent False Neurotransmitters

Carlie A. Hoffman, Meghan Bucher, Joshua M. Bradner, Lauren Jonas, Kenny Igarza, Gary W. Miller

Version 1 posted 28 August 2020

562

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Refine Search

11 results in parkinson's disease in Keywords: parkinson's disease

The Properties of α-Synuclein Secondary Nuclei are Dominated by the Solution Conditions Rather than the Seed Fibril Strain

An Anthrone-Based Kv7.2/7.3 Channel Blocker with Improved Properties for the Investigation of Psychiatric and Neurodegenerative Disorders

Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable and Blood Brain Barrier Penetrant Prote-olysis Targeting Chimera Degrader of Leucine Rich Repeat Kinase 2

Discovery and characterization of benzyloxy piperidine based dopamine 4 receptor antagonists

TD GC-MS and UPLC-MS methods to discover differentially expressed metabolites in sebum

Cyclic Ion Mobility-Mass Spectrometry and Tandem Collision Induced Unfolding for Quantification of Elusive Protein Biomarkers

Rapid Electrochemical Detection of Levodopa using Polyaniline-Modified Screen-Printed Electrodes for the Improved Management of Parkinson's Disease

Inhibition of Ubiquitin Phosphorylation by Nucleoside Analogues

Interpretable machine learning on metabolomics data reveals biomarkers for Parkinson’s disease

Assessing Vesicular Monoamine Transport and Toxicity Using Fluorescent False Neurotransmitters

11 results in Keywords: parkinson's disease