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Characterization of Monoclonal Antibody Charge Variants under Near-Native Separation Conditions using Nanoflow Sheath Liquid Capillary Electrophoresis-Mass Spectrometry

Annika A.M. van der Zon, Alisa Höchsmann, Tijmen S. Bos, Christian Neusüß, Govert W. Somsen, Kevin Jooß, Rob Haselberg, Andrea F.G. Gargano

Version 2 posted 19 July 2024

268

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Biological and Medicinal Chemistry

Working Paper

Monoclonal Antibody Bioprocess Engineering Advancements Using Conversational Artificial Intelligence

Kevin Kawchak

Version 1 posted 29 October 2024

209

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Analytical Chemistry

Working Paper

Simultaneous monitoring of monoclonal antibody variants by strong cation-exchange chromatography hyphenated to mass spectrometry to assess biosimilar-ity of rituximab-based biotherapeutics

Fiammetta Di Marco, Thomas Berger, Wolfgang Esser-Skala, Erdmann Rapp, Christof Regl, Christian G. Huber

Version 1 posted 01 July 2021

354

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Biological and Medicinal Chemistry

Working Paper

A Synthetic Glycan Array Containing Cryptococcus Neoformans Glucuronoxylomannan Capsular Polysaccharide Fragments Allows the Mapping of Protective Epitopes

Lorenzo Guazzelli, Rebecca Ulc, Anthony Bowen, Conor Crawford, Orla McCabe, Anne J. Jedlicka, Maggie P. Wear, Arturo Casadevall, Stefan Oscarson

Version 1 posted 02 March 2020

548

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2

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Chemical Education

Working Paper

Teaching biologics formulation using molecular modeling and simulations

Andrew Phillips, Anusha Srinivas, Ilina Prentoska Prentoska, Margaret O'Dea, Matthew Kustrup, Sarah Hurley, Savannah Bruno, Vy Nguyen, Pin-Kuang Lai

Version 1 posted 05 June 2023

371

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Analytical Chemistry

Working Paper

Performance Evaluation of In-source Ion Activation Hardware for Collision-Induced Unfolding of Proteins and Protein Complexes on a Drift Tube Ion Mobility-Mass Spectrometer

Varun Gadkari, Brock Juliano, Christopher Mallis, Jody May, Ruwan Kurulugama, John Fjeldsted, John McLean, David Russell, Brandon Ruotolo

Version 1 posted 05 September 2022

305

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Analytical Chemistry

Working Paper

Automated Bioanalytical Workflow for Ligand Binding Based Pharmacokinetic Assay Development

Brad Evans, Lai Yeung, Armen Beck, Annie Li, Dong Hun Lee, Gaurav Chopra, Kevin Bateman

Version 1 posted 03 March 2022

552

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Analytical Chemistry

Working Paper

Hybrid mass spectrometry applied across the production of antibody biotherapeutics.

Emilia Christofi, Mark O'Hanlon, Robin Curtis, Arghya Barman, Jeff Keen, Tibor Nagy, Perdita Barran

Version 1 posted 09 April 2024

263

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Analytical Chemistry

Working Paper

“Small is beautiful” – the significance of reliable determination of low- abundant therapeutic antibody glycovariants

Katharina Böttinger, Christof Regl, Veronika Schäpertöns, Erdmann Rapp, Therese Wohlschlager, Christian G. Huber

Version 1 posted 09 January 2024

274

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Analytical Chemistry

Working Paper

Structural Heterogeneity of the Humanised IgGk NIST Monoclonal Antibody Probed by Tandem-Trapped Ion Mobility Spectrometry and Mobility-Resolved Collision-induced Unfolding.

Fanny C. Liu, Jusung Lee, Thais Pedrete, Erin M. Panczyk, Stuart Pengelley, Christian Bleiholder

Version 2 posted 02 July 2024

219

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11 results in monoclonal antibodies in Keywords: monoclonal antibodies

Characterization of Monoclonal Antibody Charge Variants under Near-Native Separation Conditions using Nanoflow Sheath Liquid Capillary Electrophoresis-Mass Spectrometry

Monoclonal Antibody Bioprocess Engineering Advancements Using Conversational Artificial Intelligence

Simultaneous monitoring of monoclonal antibody variants by strong cation-exchange chromatography hyphenated to mass spectrometry to assess biosimilar-ity of rituximab-based biotherapeutics

A Synthetic Glycan Array Containing Cryptococcus Neoformans Glucuronoxylomannan Capsular Polysaccharide Fragments Allows the Mapping of Protective Epitopes

Teaching biologics formulation using molecular modeling and simulations

Performance Evaluation of In-source Ion Activation Hardware for Collision-Induced Unfolding of Proteins and Protein Complexes on a Drift Tube Ion Mobility-Mass Spectrometer

Automated Bioanalytical Workflow for Ligand Binding Based Pharmacokinetic Assay Development

Hybrid mass spectrometry applied across the production of antibody biotherapeutics.

“Small is beautiful” – the significance of reliable determination of low- abundant therapeutic antibody glycovariants

Structural Heterogeneity of the Humanised IgGk NIST Monoclonal Antibody Probed by Tandem-Trapped Ion Mobility Spectrometry and Mobility-Resolved Collision-induced Unfolding.

11 results in Keywords: monoclonal antibodies