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Organic Chemistry

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Stellane at the Forefront: Derivatization and Reactivity Studies of a Promising Saturated Bioisostere of ortho‐Substituted Benzenes

Oleh Smyrnov, Kostiantyn Melnykov, Olexandr Pashenko, Dmytro Volochnyuk, Serhiy Ryabukhin

Version 1 posted 18 January 2024

346

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Organic Chemistry

Working Paper

Synthesis of 3-formyl-6-azaindoles via Vilsmeier-Haack formylation of 3-amino-4-methyl pyridines

Sergey Ivonin, Volodymyr Voloshchuk, Diana Stepanova, Serhiy Ryabukhin, Dmytro Volochnyuk

Version 1 posted 14 May 2024

221

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Organic Chemistry

Working Paper

Multigram Synthesis of 4,4-disubstituted-3-oxopyrrolidones – efficient starting material for diverse 3 functionalized pyrrolidones

Semen Bondarenko, Anatolii Fedorchenko, Pavlo Novosolov, Oleksandr Marchenko, Anton Hanopolskyi, Yulian Volovenko, Dmytro Volochnyuk, Serhiy Ryabukhin

Version 1 posted 17 January 2024

249

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Organic Chemistry

Working Paper

Synthesis of 1,2,5,6- and 1,4,5,8-Anthracenetetrone: Building Blocks for π-Conjugated Small Molecules and Polymers

Florian Glöcklhofer, Berthold Stöger, Johannes Fröhlich

Version 1 posted 03 May 2018

748

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Organic Chemistry

Working Paper

Multigram Synthesis of 3-Azabicyclo[3.1.1]heptane Derivatives Including Bicyclic Thalidomide Analogs

Viacheslav Lysenko, Anton Portiankin, Oleh Shyshlyk, Timur Savchenko, Kostiantyn Nazarenko, Alexander Kostyuk, Oleksandr Golovchenko, Volodymyr Brovarets, Oleksandr Grygorenko

Version 1 posted 10 December 2024

336

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Materials Chemistry

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Data-driven discovery of organic electronic materials enabled by hybrid top-down/bottom-up design

J. Terence Blaskovits, Ruben Laplaza, Sergi Vela, Clémence Corminboeuf

Version 1 posted 05 December 2022

687

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Theoretical and Computational Chemistry

Working Paper

A close-up look at the chemical space of commercially available building blocks for medicinal chemistry

Yuliana Zabolotna, Dmitriy Volochnyuk, Sergey Ryabukhin, Dragos Horvath, Kostiantyn Gavrylenko, Gilles Marcou, Yurii Moroz, Olexandr Oksiuta, Alexandre Varnek

Version 1 posted 09 July 2021

1,523

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Organic Chemistry

Working Paper

3,3-Difluorooxetane – a Versatile Functional Group for Bioisosteric Replacements in Drug Discovery

Oleksandr Liashuk, Anastasiya Fedinchyk, Kostiantyn Melnykov, Maksym Herasymchuk, Diana Alieksieieva, Dmytro Lesyk, Yulia Bas, Tatiana Keda, Andriy Yatsymyrskiy, Yuliia Holota, Petro Borysko, Volodymyr Yarmolchuk, Oleksandr Grygorenko

Version 1 posted 14 August 2024

1,264

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Organic Chemistry

Working Paper

Synthesis of 6-azaindoles via electrophilic [4+1]-cyclization of 3-amino-4-methyl pyridines: scope and limitations

Sergey Ivonin, Volodymyr Voloshchuk, Eduard Rusanov, Sergey Suikov, Serhiy Ryabukhin, Dmytro Volochnyuk

Version 1 posted 31 July 2023

272

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Organic Chemistry

Working Paper

Oxetane as a part of modern medicinal chemistry toolbox: the case of 3,3-disubstituted building blocks

Eduard Litskan, Oleksandr Semenchenko, Serhii Lynnyk, Dmitry Granat, Bohdan Vashchenko, Anastasiia Hoida, Daria Tolmachova, Dmytro Leha, Oleksandr Grygorenko, Dmytro Volochnyuk, Serhiy Ryabukhin

Version 1 posted 12 November 2024

1,530

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13 results in building blocks in Keywords: building blocks

Stellane at the Forefront: Derivatization and Reactivity Studies of a Promising Saturated Bioisostere of ortho‐Substituted Benzenes

Synthesis of 3-formyl-6-azaindoles via Vilsmeier-Haack formylation of 3-amino-4-methyl pyridines

Multigram Synthesis of 4,4-disubstituted-3-oxopyrrolidones – efficient starting material for diverse 3 functionalized pyrrolidones

Synthesis of 1,2,5,6- and 1,4,5,8-Anthracenetetrone: Building Blocks for π-Conjugated Small Molecules and Polymers

Multigram Synthesis of 3-Azabicyclo[3.1.1]heptane Derivatives Including Bicyclic Thalidomide Analogs

Data-driven discovery of organic electronic materials enabled by hybrid top-down/bottom-up design

A close-up look at the chemical space of commercially available building blocks for medicinal chemistry

3,3-Difluorooxetane – a Versatile Functional Group for Bioisosteric Replacements in Drug Discovery

Synthesis of 6-azaindoles via electrophilic [4+1]-cyclization of 3-amino-4-methyl pyridines: scope and limitations

Oxetane as a part of modern medicinal chemistry toolbox: the case of 3,3-disubstituted building blocks

13 results in Keywords: building blocks