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Chemical Engineering and Industrial Chemistry

Working Paper

Process Development and Scale-Up of the SOS1 Inhibitor MRTX0902

Thomas Scattolin, Joseph Lizza, Cheng-yi Chen

Version 1 posted 05 January 2023

825

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Physical Chemistry

Working Paper

Experimental and Topological Determination of the Pressure-Temperature Phase Diagram of Racemic Etifoxine, a Pharmaceutical Ingredient with Anxiolytic Properties

Maria Barrio, Hassan Allouchi, Josep-Lluis Tamarit, René Céolin, L Berthon-Cédille, Ivo Rietveld

Version 1 posted 13 November 2019

263

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Physical Chemistry

Working Paper

The Phase Relationship Between the Pyrazinamide Polymorphs α and γ

Kangli Li, Gabin Gbabode, Maria Barrio, Josep-Lluis Tamarit, Marine Vergé-Depré, Benoît Robert, Ivo Rietveld

Version 1 posted 23 December 2019

419

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Organic Chemistry

Working Paper

Amidation by Reactive Extrusion for the Synthesis of Active Pharmaceutical Ingredients Teriflunomide and Moclobemide

Matthieu Lavayssiere, Frédéric Lamaty

Version 3 posted 21 December 2022

399

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Chemical Engineering and Industrial Chemistry

Working Paper

Development of Adagrasib’s Commercial Manufacturing Route

David Snead, Yonghong Gan, Thomas Scattolin, Dinesh Paymode, Michal Achmatowicz, Duane Rudisill, Ephraim Vidal, Tawfik Gharbaoui, Phil Roberts, Jianbo Yang, Zhangbing Shi, Wei Liu, Joshua Bolger, Zhen Qiao, Cheng-yi Chen

Version 1 posted 13 December 2022

2,266

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3

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Organic Chemistry

Working Paper

Atom-efficient direct amidation by thermo-mechanochemistry

Tomislav Stolar, Jasna Alić, Nikola Cindro, Krešimir Molčanov, Krunoslav Užarević, José G. Hernández

Version 1 posted 07 June 2023

512

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Physical Chemistry

Working Paper

Unveiling polyamorphism and polyamorphic interconversions in pharmaceuticals: the peculiar case of hydrochlorothiazide

Inês C. B Martins, Anders S. Larsen, Anders Ø. Madsen, Olivia Aalling Frederiksen, Kirsten M. Ø. Jensen, Henrik S. Jeppesen, Thomas Rades

Version 1 posted 08 June 2023

332

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Chemical Engineering and Industrial Chemistry

Working Paper

Simultaneous Processing of Antagonistic Chemical Events (SPACE): An Atroposelective Dynamic Kinetic Resolution of MRTX1719

Michal Achmatowicz, Cheng-yi Chen, David Snead

Version 2 posted 20 June 2022

1,440

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2

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Organic Chemistry

Working Paper

Improved Access to Cyclopropanol via Supply-Centered Synthesis

David Snead, Cheng-yi Chen

Version 1 posted 12 September 2022

583

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1

Citations

Analytical Chemistry

Working Paper

SEISMiQ: de novo impurity structure elucidation from tandem mass spectra boosts drug development

Emilio Dorigatti, Jonathan Groß, Jonas Kühlborn, Robert Möckel, Frank Maier, Julian Keupp

Version 1 posted 04 March 2025

238

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10 results in active pharmaceutical ingredient in Keywords: active pharmaceutical ingredient

Process Development and Scale-Up of the SOS1 Inhibitor MRTX0902

Experimental and Topological Determination of the Pressure-Temperature Phase Diagram of Racemic Etifoxine, a Pharmaceutical Ingredient with Anxiolytic Properties

The Phase Relationship Between the Pyrazinamide Polymorphs α and γ

Amidation by Reactive Extrusion for the Synthesis of Active Pharmaceutical Ingredients Teriflunomide and Moclobemide

Development of Adagrasib’s Commercial Manufacturing Route

Atom-efficient direct amidation by thermo-mechanochemistry

Unveiling polyamorphism and polyamorphic interconversions in pharmaceuticals: the peculiar case of hydrochlorothiazide

Simultaneous Processing of Antagonistic Chemical Events (SPACE): An Atroposelective Dynamic Kinetic Resolution of MRTX1719

Improved Access to Cyclopropanol via Supply-Centered Synthesis

SEISMiQ: de novo impurity structure elucidation from tandem mass spectra boosts drug development

10 results in Keywords: active pharmaceutical ingredient