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Biological and Medicinal Chemistry

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Organic Chemistry

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Site-specific conjugation technology

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4 results in Keywords: Site-specific conjugation technology

Biological and Medicinal Chemistry

Biological Evaluation of Cleavable Linkers in Exatecan-Based Antibody-Drug Conjugates: A Comparative Study of DXd and Exo-Linker Platforms

Tomohiro Watanabe, Yusuke Iwai, Natsuki Shikida, Jason T. Stofleth, Takuya Seki, Kazutaka Shimbo, Yutaka Matsuda

Version 1 posted 24 December 2024

0

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Biological and Medicinal Chemistry

Bispecific Antibodies Produced via Chemical Site-Specific Conjugation Technology: AJICAP Second Generation

Tomohiro Fujii, Kenichiro Ito, Kazutoshi Takahashi, Tsubasa Aoki, Takuya Seki, Yusuke Iwai, Rika Takasugi, Tomohiro Watanabe, Ryusuke Hirama, Ryo Tsumura, Hirobumi Fuchigami, Masahiro Yasunaga, Yutaka Matsuda

Version 1 posted 25 August 2023

352

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Organic Chemistry

Gram-Scale Synthesis of Site-Specific Antibody-Drug Conjugates Using AJICAP Second-Generation Technology

Tomohiro Watanabe, Tomohiro Fujii, Jason Stofleth, Rika Takasugi, Kazutoshi Takahashi, Yutaka Matsuda

Version 1 posted 05 April 2023

605

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2

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Organic Chemistry

Enhanced Chemical Method for Bispecific Antibody Production: Leveraging Site-Specific Conjugation and Stable Crosslinker Technology

Tomohiro Fujii, Yutaka Matsuda

Version 2 posted 02 December 2024

219

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