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Proteolysis targeting chimera

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2 results in Keywords: Proteolysis targeting chimera

Biological and Medicinal Chemistry

Leveraging dual-ligase recruitment to enhance degradation via a heterotrivalent PROTAC

Adam G. Bond, Miquel Muñoz i Ordoño, Celia M. Bisbach, Conner Craigon, Nikolai Makukhin, Elizabeth A. Caine, Manjula Nagala, Marjeta Urh, Georg E. Winter, Kristin M. Riching, Alessio Ciulli

Version 1 posted 21 August 2024

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Biological and Medicinal Chemistry

Chemoproteomics-Enabled De Novo Discovery of Metallothionein Degraders Facilitates Probing Its Role in Cancer

Brittney Racioppo, Dany Pechalrieu, Daniel Abegg, Brendan Dwyer, Neal Ramseier, Ying Hu, Alexander Adibekian

Version 2 posted 13 August 2024

559

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