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Enhancing Binding Affinity of an Intrinsically Disordered Protein by α-Methylation of Key Amino Acid Residues

Valentin Bauer, Boris Schmidtgall, Gergő Gógl, Jozica Dolenc, Judit Osz, Yves Nominé, Camille Kostmann, Alexandra Cousido-Siah, André Mitschler, Natacha Rochel, Gilles Travé, Bruno Kieffer, Vladimir Torbeev

Version 1 posted 06 November 2019

879

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Physical Chemistry

Working Paper

Combining Site-Directed Spin Labeling in Vivo and In-Cell EPR Distance Determination

Pia Widder, Julian Schuck, Daniel Summerer, Malte Drescher

Version 1 posted 30 August 2019

611

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Physical Chemistry

Working Paper

Protein Spin Labeling with a Photocaged Nitroxide Using Diels-Alder Chemistry

Anandi Kugele, Bjarne Silkenath, Jakob Langer, Valentin Wittmann, Malte Drescher

Version 1 posted 02 April 2019

423

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Catalysis

Working Paper

Biocatalytic asymmetric aldol addition into unactivated ketones

Samantha Bruffy, Anthony Meza, Jordi Soler, Tyler Doyon, Seth Young, Jooyeon Lim, Kathryn Huseth, Marc Garcia-Borràs, Andrew Buller

Version 1 posted 02 November 2023

693

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1

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Catalysis

Working Paper

A Genetically Encoded Thiophenol Recruits Noble Metals for Designer Enzymes

Mathijs J. Veen, Friso S. Aalbers, Henriëtte J. Rozeboom, Andy-Mark W. H. Thunnissen, Daniel F. Sauer, Gerard Roelfes

Version 1 posted 22 July 2024

406

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Biological and Medicinal Chemistry

Working Paper

Diversifying Amino Acids and Peptides via Deaminative Reductive Cross-Couplings Leveraging High-Throughput Experimentation

J. Cameron Twitty, Yun Hong, Bria Garcia, Stephanie Tsang, Jennie Liao, Danielle Schultz, Amelie Dion, Dipannita Kalyani, Mary Watson

Version 1 posted 21 March 2022

1,115

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Catalysis

Working Paper

Tandem Friedel-Crafts-Alkylation-Enantioselective-Protonation by Artificial Enzyme Iminium Catalysis

Reuben Leveson-Gower, Ruben de Boer, Gerard Roelfes

Version 1 posted 03 November 2021

416

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Catalysis

Working Paper

Synergistic Catalysis of Tandem Michael Addition/Enantioselective Protonation Reactions by an Artificial Enzyme

Zhi Zhou, Gerard Roelfes

Version 1 posted 09 April 2021

390

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Catalysis

Working Paper

Unlocking Iminium Catalysis in Artificial Enzymes to Create a Friedel-Crafts Alkylase

Reuben B. Leveson-Gower, Zhi Zhou, Ivana Drienovská, Gerard Roelfes

Version 1 posted 19 February 2021

529

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Biological and Medicinal Chemistry

Working Paper

Use of Non-canonical Tyrosine Analogs to Probe Control of Radical Intermediates during Endoperoxide Installation by Verruculogen Synthase (FtmOx1)

Chi-Yun Lin, Angel L. Muñoz, Tatiana N. Laremore, Alexey Silakov, Carsten Krebs, Amie K. Boal, J. Martin Bollinger, Jr.

Version 1 posted 21 February 2022

422

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13 results in Non-canonical amino acids in Keywords: Non-canonical amino acids

Enhancing Binding Affinity of an Intrinsically Disordered Protein by α-Methylation of Key Amino Acid Residues

Combining Site-Directed Spin Labeling in Vivo and In-Cell EPR Distance Determination

Protein Spin Labeling with a Photocaged Nitroxide Using Diels-Alder Chemistry

Biocatalytic asymmetric aldol addition into unactivated ketones

A Genetically Encoded Thiophenol Recruits Noble Metals for Designer Enzymes

Diversifying Amino Acids and Peptides via Deaminative Reductive Cross-Couplings Leveraging High-Throughput Experimentation

Tandem Friedel-Crafts-Alkylation-Enantioselective-Protonation by Artificial Enzyme Iminium Catalysis

Synergistic Catalysis of Tandem Michael Addition/Enantioselective Protonation Reactions by an Artificial Enzyme

Unlocking Iminium Catalysis in Artificial Enzymes to Create a Friedel-Crafts Alkylase

Use of Non-canonical Tyrosine Analogs to Probe Control of Radical Intermediates during Endoperoxide Installation by Verruculogen Synthase (FtmOx1)

13 results in Keywords: Non-canonical amino acids