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Biocatalytic asymmetric aldol addition into unactivated ketones

Samantha Bruffy, Anthony Meza, Jordi Soler, Tyler Doyon, Seth Young, Jooyeon Lim, Kathryn Huseth, Marc Garcia-Borràs, Andrew Buller

Version 1 posted 02 November 2023

693

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Catalysis

Working Paper

Boron Catalysis in a Designer Enzyme

Lars Longwitz, Reuben B. Leveson-Gower, Henriëtte J. Rozeboom, Andy-Mark W. H. Thunnissen, Gerard Roelfes

Version 1 posted 27 September 2023

1,154

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Catalysis

Working Paper

Evolutionary Specialisation of a Promiscuous Artificial Enzyme

Reuben B. Leveson-Gower, Laura Tiessler-Sala, Henriëtte J. Rozeboom, Andy-Mark W.H. Thunnissen, Jean-Didier Maréchal, Gerard Roelfes

Version 1 posted 02 September 2024

364

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Catalysis

Working Paper

Synergistic Photoenzymatic Catalysis Enables Synthesis of a-Tertiary Amino Acids Using Threonine Aldolases

Yao Ouyang, Claire Page, Catherine Bilodeau, Todd Hyster

Version 1 posted 06 May 2024

1,209

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Catalysis

Working Paper

A Genetically Encoded Thiophenol Recruits Noble Metals for Designer Enzymes

Mathijs J. Veen, Friso S. Aalbers, Henriëtte J. Rozeboom, Andy-Mark W. H. Thunnissen, Daniel F. Sauer, Gerard Roelfes

Version 1 posted 22 July 2024

406

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Biological and Medicinal Chemistry

Working Paper

Enhancing Binding Affinity of an Intrinsically Disordered Protein by α-Methylation of Key Amino Acid Residues

Valentin Bauer, Boris Schmidtgall, Gergő Gógl, Jozica Dolenc, Judit Osz, Yves Nominé, Camille Kostmann, Alexandra Cousido-Siah, André Mitschler, Natacha Rochel, Gilles Travé, Bruno Kieffer, Vladimir Torbeev

Version 1 posted 06 November 2019

879

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Physical Chemistry

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Combining Site-Directed Spin Labeling in Vivo and In-Cell EPR Distance Determination

Pia Widder, Julian Schuck, Daniel Summerer, Malte Drescher

Version 1 posted 30 August 2019

611

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Catalysis

Working Paper

Synergistic Catalysis of Tandem Michael Addition/Enantioselective Protonation Reactions by an Artificial Enzyme

Zhi Zhou, Gerard Roelfes

Version 1 posted 09 April 2021

390

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Biological and Medicinal Chemistry

Working Paper

Use of Non-canonical Tyrosine Analogs to Probe Control of Radical Intermediates during Endoperoxide Installation by Verruculogen Synthase (FtmOx1)

Chi-Yun Lin, Angel L. Muñoz, Tatiana N. Laremore, Alexey Silakov, Carsten Krebs, Amie K. Boal, J. Martin Bollinger, Jr.

Version 1 posted 21 February 2022

422

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Biological and Medicinal Chemistry

Working Paper

Diversifying Amino Acids and Peptides via Deaminative Reductive Cross-Couplings Leveraging High-Throughput Experimentation

J. Cameron Twitty, Yun Hong, Bria Garcia, Stephanie Tsang, Jennie Liao, Danielle Schultz, Amelie Dion, Dipannita Kalyani, Mary Watson

Version 1 posted 21 March 2022

1,115

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13 results in Non-canonical Amino Acids in Keywords: Non-canonical Amino Acids

Biocatalytic asymmetric aldol addition into unactivated ketones

Boron Catalysis in a Designer Enzyme

Evolutionary Specialisation of a Promiscuous Artificial Enzyme

Synergistic Photoenzymatic Catalysis Enables Synthesis of a-Tertiary Amino Acids Using Threonine Aldolases

A Genetically Encoded Thiophenol Recruits Noble Metals for Designer Enzymes

Enhancing Binding Affinity of an Intrinsically Disordered Protein by α-Methylation of Key Amino Acid Residues

Combining Site-Directed Spin Labeling in Vivo and In-Cell EPR Distance Determination

Synergistic Catalysis of Tandem Michael Addition/Enantioselective Protonation Reactions by an Artificial Enzyme

Use of Non-canonical Tyrosine Analogs to Probe Control of Radical Intermediates during Endoperoxide Installation by Verruculogen Synthase (FtmOx1)

Diversifying Amino Acids and Peptides via Deaminative Reductive Cross-Couplings Leveraging High-Throughput Experimentation

13 results in Keywords: Non-canonical Amino Acids