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Catalysis

Working Paper

Electrostatic Assistance of 4-Mercaptophenylacetic acid catalyzed Native Chemical Ligation

Nathalie Ollivier, Eliott Roy, Rémi Desmet, Vangelis Agouridas, Vincent Diemer, Oleg Melnyk

Version 1 posted 10 March 2023

409

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1

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Biological and Medicinal Chemistry

Working Paper

Azole reagents enabled ligation of peptide acyl pyrazoles for chemical protein synthesis

Peisi Liao, Chunmao He

Version 2 posted 13 December 2023

518

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Biological and Medicinal Chemistry

Working Paper

Rapid building block-economic synthesis of long, multi-O-GalNAcylated MUC5AC tandem repeat peptides

Arseniy Galashov, Ekaterina Kazakova, Christian Stieger, Christian Hackenberger, Oliver Seitz

Version 1 posted 18 September 2023

330

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Biological and Medicinal Chemistry

Working Paper

N-terminal cysteine as minimalistic handle for dual, site-selective bioconjugation: application to an anti-HER2 affibody reveals synergy of two conjugated drugs

Ana Novak, Florian Kersaudy, Sylvie Berger, Séverine Morisset-Lopez, François Lefoulon, Carlo Pifferi, Vincent Aucagne

Version 2 posted 15 May 2023

659

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Organic Chemistry

Working Paper

Utilizing Copper-Mediated Deprotection of Selenazolidine for Cyclic Peptides Synthesis

Zhenguang Zhao, Norman Metanis

Version 1 posted 01 October 2019

802

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Biological and Medicinal Chemistry

Working Paper

Selenolysine: A New Tool for Traceless Isopeptide Bond Formation

Rebecca Notis Dardashti, Shailesh Kumar, Shawn M. Sternisha, Post Sai Reddy, Brian G. Miller, Norman Metanis

Version 1 posted 24 December 2019

618

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Organic Chemistry

Working Paper

Reinvestigation of a Critical Reductive Amination Step Leads to an Optimized Protocol for the Synthesis of N-2-Hydroxybenzylcysteine Peptide Crypto-Thioesters

Skander Abboud, Vincent AUCAGNE

Version 3 posted 24 August 2020

927

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Biological and Medicinal Chemistry

Working Paper

Copper-mediated selenazolidine deprotection enables one-pot chemical synthesis of challenging proteins

Zhenguang Zhao, Norman Metanis

Version 1 posted 23 July 2019

865

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Catalysis

Working Paper

Insights into the Mechanism and Catalysis of Peptide Thioester Synthesis by Alkylselenols Provide a New Tool for Chemical Protein Synthesis

Florent kerdraon, Gemma Bogard, Benoît Snella, Hervé Drobecq, Muriel Pichavant, Vangelis Agouridas, Oleg Melnyk

Version 1 posted 11 February 2021

379

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Biological and Medicinal Chemistry

Working Paper

N-Terminal Proline Editing for the Synthesis of Peptides with Mercaptoproline and Selenoproline: Mechanistic Insights Lead to Greater Efficiency in Proline Native Chemical Ligation

Brice Ludwig, Christina Forbes, Neal Zondlo

Version 1 posted 17 January 2023

387

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Refine Search

26 results in Native chemical ligation in Keywords: Native chemical ligation

Electrostatic Assistance of 4-Mercaptophenylacetic acid catalyzed Native Chemical Ligation

Azole reagents enabled ligation of peptide acyl pyrazoles for chemical protein synthesis

Rapid building block-economic synthesis of long, multi-O-GalNAcylated MUC5AC tandem repeat peptides

N-terminal cysteine as minimalistic handle for dual, site-selective bioconjugation: application to an anti-HER2 affibody reveals synergy of two conjugated drugs

Utilizing Copper-Mediated Deprotection of Selenazolidine for Cyclic Peptides Synthesis

Selenolysine: A New Tool for Traceless Isopeptide Bond Formation

Reinvestigation of a Critical Reductive Amination Step Leads to an Optimized Protocol for the Synthesis of N-2-Hydroxybenzylcysteine Peptide Crypto-Thioesters

Copper-mediated selenazolidine deprotection enables one-pot chemical synthesis of challenging proteins

Insights into the Mechanism and Catalysis of Peptide Thioester Synthesis by Alkylselenols Provide a New Tool for Chemical Protein Synthesis

N-Terminal Proline Editing for the Synthesis of Peptides with Mercaptoproline and Selenoproline: Mechanistic Insights Lead to Greater Efficiency in Proline Native Chemical Ligation

26 results in Keywords: Native chemical ligation