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Lessons for Oral Bioavailability: How Conformationally Flexible Cyclic Peptides Enter and Cross Lipid Membranes

Stephanie M. Linker, Christian Schellhaas, Anna S. Kamenik, Hans-Joerg Roth, Marianne Fouche, Stephane Rodde, Sereina Riniker

Version 1 posted 08 November 2022

684

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Biological and Medicinal Chemistry

Working Paper

Synthetic Studies with the Brevicidine and Laterocidine Lipopeptide Antibiotics Including Analogues with Enhanced Properties and in vivo Efficacy

Karol Al-Ayed, Ross D. Ballantine, Michael Hoekstra, Samantha Bann, Charlotte Wesseling, Alexander Bakker, Zheng Zhong, Yongxin Li, Mario van der Stelt, Stephen Cochrane, Nathaniel Martin

Version 2 posted 10 January 2022

1,200

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Theoretical and Computational Chemistry

Working Paper

Understanding Ring Puckering in Small Molecules and Cyclic Peptides

Lucian Chan, Geoffrey Hutchison, Garrett Morris

Version 1 posted 25 September 2020

1,050

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Catalysis

Working Paper

Electrochemical Nickel-Catalyzed Selective Arylation of Cysteine-Containing Peptides

Samir MESSAOUDI, Shen Linhua, Olivier Monasson, Elisa Peroni, Franck Le bideau

Version 1 posted 08 June 2023

527

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Biological and Medicinal Chemistry

Working Paper

Cyclic Peptides as Aggregation Inhibitors for Sickle Cell Disease

Vasco Neto, Bruno Victor, Nuno Galamba

Version 1 posted 13 October 2023

232

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Biological and Medicinal Chemistry

Working Paper

Merging Flow Synthesis and Enzymatic Maturation to Expand the Chemical Space of Lasso Peptides

Kevin Schiefelbein, Jakob Lang, Matthias Schuster, Claire Grigglestone, Robin Striga, Laurent Bigler, Meredith C. Schuman, Oliver Zerbe, Yanyan Li, Nina Hartrampf

Version 1 posted 20 March 2024

709

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Biological and Medicinal Chemistry

Working Paper

Identification of photocrosslinking peptide ligands by mRNA display

Yuteng Wu, M. Teresa Bertran, Dhira Joshi, Sarah Maslen, Catherine Hurd, Louise Walport

Version 1 posted 07 October 2021

648

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Organic Chemistry

Working Paper

Chemoselective, oxidation-induced macrocyclization of tyrosine-containing peptides

E. Dalles Keyes, Marcus C. Mifflin, Maxwell J. Austin, Brighton J. Alvey, Lotfa H. Lovely, Andriea Smith, Bethany A. Buck-Koehntop, Andrew G. Roberts

Version 2 posted 05 January 2023

880

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Theoretical and Computational Chemistry

Working Paper

Dock-able linear and homodetic di, tri, tetra and pentapeptide library from canonical amino acids: SARS-CoV-2 Mpro as a case study

Sarfraz Ahmad, M. Usman Mirza, John Trant

Version 1 posted 06 January 2023

236

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Biological and Medicinal Chemistry

Working Paper

A Phage-Compatible Strategy to Access Macrocyclic Peptides Featuring Asymmetric Molecular Scaffolds as Cyclization Units

Titia Rixt Oppewal, Johan Hekelaar, Clemens Mayer

Version 1 posted 04 February 2021

740

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18 results in Cyclic peptides in Keywords: Cyclic peptides

Lessons for Oral Bioavailability: How Conformationally Flexible Cyclic Peptides Enter and Cross Lipid Membranes

Synthetic Studies with the Brevicidine and Laterocidine Lipopeptide Antibiotics Including Analogues with Enhanced Properties and in vivo Efficacy

Understanding Ring Puckering in Small Molecules and Cyclic Peptides

Electrochemical Nickel-Catalyzed Selective Arylation of Cysteine-Containing Peptides

Cyclic Peptides as Aggregation Inhibitors for Sickle Cell Disease

Merging Flow Synthesis and Enzymatic Maturation to Expand the Chemical Space of Lasso Peptides

Identification of photocrosslinking peptide ligands by mRNA display

Chemoselective, oxidation-induced macrocyclization of tyrosine-containing peptides

Dock-able linear and homodetic di, tri, tetra and pentapeptide library from canonical amino acids: SARS-CoV-2 Mpro as a case study

A Phage-Compatible Strategy to Access Macrocyclic Peptides Featuring Asymmetric Molecular Scaffolds as Cyclization Units

18 results in Keywords: Cyclic peptides