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A Positive Charge in an Antimalarial Compound Unlocks Broad-spectrum Antibacterial Activity

Maria Braun-Cornejo, Mitchell Platteschorre, Vincent de Vries, Patricia Bravo, Vidhisha Sonawane, Mostafa M. Hamed, Jörg Haupenthal, Norbert Reiling, Matthias Rottmann, Dennis Piet, Peter Maas, Eleonora Diamanti, Anna K. H. Hirsch

Version 2 posted 03 June 2024

225

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Nanoscience

Review

Overview of nanotherapeutics for bacterial infections

José Muñoz-López, Cátia D. F. Lopes, Iris L. Batalha

Version 1 posted 06 February 2024

268

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Biological and Medicinal Chemistry

Working Paper

Chasing new targets to fight antimicrobial resistance: identification of small molecules affecting the interaction of human hemoglobin with the IsdB hemophore of Staphylococcus aureus

Monica Cozzi, Maria Cristina Failla, Eleonora Gianquinto, Sandra Kovachka, Valeria Buoli Comani, Carlotta Compari, Omar De Bei, Roberta Giaccari, Francesco Marchesani, Marialaura Marchetti, Luca Ronda, Barbara Rolando, Massimo Baroni, Gabriele Cruciani, Barbara Campanini, Stefano Bettati, Serena Faggiano, Loretta Lazzarato, Francesca Spyrakis

Version 1 posted 31 January 2024

151

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Analytical Chemistry

Working Paper

A minimally instrumented method for the detection of rifampicin resistance-causing mutations in Mycobacterium tuberculosis utilizing lateral flow readout

Ayushi Chauhan, S SivaKumar, Bhushan Toley

Version 1 posted 20 August 2024

138

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Biological and Medicinal Chemistry

Review

Therapeutic synthetic anion transporters

Elba Feo, Philip Alan Gale

Version 1 posted 17 July 2024

245

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Biological and Medicinal Chemistry

Working Paper

Inhibitors of the Elastase LasB for the treatment of Pseudomonas aeruginosa lung infections

Jelena Konstantinovic, Andreas M. Kany, Alaa Alhayek, Ahmed S. Abdelsamie, Asfandyar Sikandar, Katrin Voos, Yiwen Yao, Anastasia Andreas, Roya Shafiei, Brigitta Loretz, Esther Schönauer, Robert Bals, Hans Brandstetter, Rolf W. Hartmann, Christian Ducho, Claus-Michael Lehr, Christoph Beisswenger, Rolf Müller, Katharina Rox, Jörg Haupenthal, Anna Katharina Herta Hirsch

Version 1 posted 24 April 2023

382

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Biological and Medicinal Chemistry

Working Paper

Using Machine Learning to Predict the Antibacterial Activity of Ruthenium Complexes

Markus Orsi, Boon Shing Loh, Cheng Weng, Wee Han Ang, Angelo Frei

Version 2 posted 23 November 2023

664

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Biological and Medicinal Chemistry

Review

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Paolo Rossetti, Marius Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer Böckmann

Version 2 posted 03 December 2024

283

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Biological and Medicinal Chemistry

Working Paper

De Novo Design of Type II Topoisomerase Inhibitors as Potential Antimicrobial Agents Targeting a Novel Binding Region

Kyle Orritt, Juliette Newell, Lipeng Feng, Thomas Germe, Lauren Abbott, Holly Jackson, Benjamin Bury, Anthony Maxwell, Martin McPhillie, Colin Fishwick

Version 2 posted 16 December 2021

497

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Biological and Medicinal Chemistry

Working Paper

Riboflavin-Vancomycin Conjugate Enables Simultaneous Antibiotic Photo-Release and Photodynamic Killing against Resistant Gram-Positive Pathogens

Bethany Mills, Alex Kiang, Syam Mohan P. C. Mohanan, Mark Bradley, Maxime Klausen

Version 2 posted 19 May 2023

265

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16 results in Antimicrobial resistance in Keywords: Antimicrobial resistance

A Positive Charge in an Antimalarial Compound Unlocks Broad-spectrum Antibacterial Activity

Overview of nanotherapeutics for bacterial infections

Chasing new targets to fight antimicrobial resistance: identification of small molecules affecting the interaction of human hemoglobin with the IsdB hemophore of Staphylococcus aureus

A minimally instrumented method for the detection of rifampicin resistance-causing mutations in Mycobacterium tuberculosis utilizing lateral flow readout

Therapeutic synthetic anion transporters

Inhibitors of the Elastase LasB for the treatment of Pseudomonas aeruginosa lung infections

Using Machine Learning to Predict the Antibacterial Activity of Ruthenium Complexes

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

De Novo Design of Type II Topoisomerase Inhibitors as Potential Antimicrobial Agents Targeting a Novel Binding Region

Riboflavin-Vancomycin Conjugate Enables Simultaneous Antibiotic Photo-Release and Photodynamic Killing against Resistant Gram-Positive Pathogens

16 results in Keywords: Antimicrobial resistance