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Biological and Medicinal Chemistry

Working Paper

A Study with Peptide Dendrimers Reveals an Extreme pH Dependence of Antibiotic Activity Above pH 7.4

Xingguang Cai, Sacha Javor, Bee-Ha Gan, Thilo Köhler, Jean-Louis Reymond

Version 3 posted 01 April 2021

467

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Analytical Chemistry

Working Paper

Investigating Antimicrobial Peptide-Membrane Interactions Using Fast Photochemical Oxidation of Peptides in Nanodiscs

Deseree Reid, James Rohrbough, Marius Kostelic, Michael Marty

Version 1 posted 23 August 2021

403

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Theoretical and Computational Chemistry

Working Paper

Free Energy Analysis of Peptide-Induced Pore Formation in Lipid Membranes by Bridging Atomistic and Coarse-Grained Simulations

Joshua Richardson, Reid Van Lehn

Version 1 posted 20 May 2024

208

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Biological and Medicinal Chemistry

Working Paper

Exploring the Chemical Space of Antiparasitic Peptides and Discovery of New Promising Leads through a Novel Approach based on Network Science and Similarity Searching

Sebastián Ayala-Ruano, Yovani Marrero-Ponce, Longendri Aguilera‑Mendoza, Noel Pérez, Guillermin Agüero-Chapin, Agostinho Antunes, Ana Cristina Aguilar

Version 2 posted 11 February 2022

563

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Biological and Medicinal Chemistry

Working Paper

Design of antimicrobial peptides containing non-proteinogenic amino acids using multi-objective Bayesian optimisation

Yuki Murakami, Shoichi Ishida, Yosuke Demizu, Kei Terayama

Version 2 posted 15 May 2023

264

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Biological and Medicinal Chemistry

Working Paper

Machine Learning Designs Non-Hemolytic Antimicrobial Peptides

Alice Capecchi, Xingguang Cai, Hippolyte Personne, Thilo Köhler, Christian van Delden, Jean-Louis Reymond

Version 1 posted 18 March 2021

661

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Biological and Medicinal Chemistry

Working Paper

Can Large Language Models Predict Antimicrobial Peptide Activity and Toxicity?

Markus Orsi, Jean-Louis Reymond

Version 2 posted 12 March 2024

790

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Analytical Chemistry

Working Paper

Label-free measurement of antimicrobial peptide interactions with lipid vesicles and nanodiscs using microscale thermophoresis

Philip Rainsford, Fredrik Rylandsholm, Martin Jakubec, Eric Juskewitz, Mitchell Silk, Richard A. Engh, Johan Isaksson

Version 2 posted 11 November 2022

307

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1

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Biological and Medicinal Chemistry

Working Paper

Mixed Chirality α-Helix in a Stapled Bicyclic and a Linear Antimicrobial Peptide Revealed by X-Ray Crystallography

stéphane Baeriswyl, Hippolyte Personne, Ivan Di Bonaventura, Thilo Köhler, Christian van Delden, Achim Stocker, Sacha Javor, Jean-Louis Reymond

Version 3 posted 13 May 2021

718

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Nanoscience

Working Paper

Peptide-conjugated phage-mimicking nanoparticles exhibit potent antibacterial action against Streptococcus pyogenes in murine wound infection models

Johanna Olesk, Deborah Donahue, Jessica Ross, Conor Sheehan, Zach Bennett, Kevin Armknecht, Carlie Kudary, Juliane Hopf, Victoria A. Ploplis, Francis J. Castellino, Shaun W. Lee, Prakash Nallathamby

Version 1 posted 02 June 2023

241

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12 results in Antimicrobial Peptides in Keywords: Antimicrobial Peptides

A Study with Peptide Dendrimers Reveals an Extreme pH Dependence of Antibiotic Activity Above pH 7.4

Investigating Antimicrobial Peptide-Membrane Interactions Using Fast Photochemical Oxidation of Peptides in Nanodiscs

Free Energy Analysis of Peptide-Induced Pore Formation in Lipid Membranes by Bridging Atomistic and Coarse-Grained Simulations

Exploring the Chemical Space of Antiparasitic Peptides and Discovery of New Promising Leads through a Novel Approach based on Network Science and Similarity Searching

Design of antimicrobial peptides containing non-proteinogenic amino acids using multi-objective Bayesian optimisation

Machine Learning Designs Non-Hemolytic Antimicrobial Peptides

Can Large Language Models Predict Antimicrobial Peptide Activity and Toxicity?

Label-free measurement of antimicrobial peptide interactions with lipid vesicles and nanodiscs using microscale thermophoresis

Mixed Chirality α-Helix in a Stapled Bicyclic and a Linear Antimicrobial Peptide Revealed by X-Ray Crystallography

Peptide-conjugated phage-mimicking nanoparticles exhibit potent antibacterial action against Streptococcus pyogenes in murine wound infection models

12 results in Keywords: Antimicrobial Peptides