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Biological and Medicinal Chemistry

Working Paper

Amyloid Capture and Aggregation Inhibition by Human Serum Albumin

Diego Cora, Wajih Al-Soufi, Mercedes Novo

Version 1 posted 23 December 2024

0

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Biological and Medicinal Chemistry

Working Paper

Amentoflavone: A Bifunctional Metal Chelator that Controls the Formation of Neurotoxic Soluble Aβ42 Oligomers

Liang Sun, Anuj K. Sharma, Byung-Hee Han, Liviu M. Mirica

Version 1 posted 09 June 2020

386

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Analytical Chemistry

Working Paper

Amyloid Plaque Polymorphism is Associated with Distinct Lipid Accumulations Revealed by Trapped Ion Mobility Mass Spectrometry Imaging (TIMS MSI)

Wojciech Michno, Patrick Wehrli, Srinivas Koutarapu, Christian Marsching, Karolina Minta, Junyue Ge, Sven Meyer, Henrik Zetterberg, Kaj Blennow, Corinna Henkel, Janina Oetjen, Carsten Hopf, Jörg Hanrieder

Version 1 posted 19 October 2021

261

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Biological and Medicinal Chemistry

Working Paper

Contilistat, a new polyfunctionalized histone deacetylase inhibitor, showing potential capacity to inhibit cholinesterase/monoamine oxidase enzymes, and modulate histamine 3, sigma 1, 5-HT6 and dopamine 3 receptors for the treatment of cancer and neurodegenerative diseases

José Marco-Contelles, Daniel Diez-Iriepa, Mireia Toledano-Pinedo, Alicia Porro, Pedro Almendros, M. Mercedes Rodríguez-Fernández,, Abdelouahid Samadi, Isabel Iriepa, Francisco López-Muñoz, Aizpea Artetxe-Zurutuza, Ander Matheu

Version 1 posted 12 May 2023

266

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Inorganic Chemistry

Working Paper

Zn(II)-Driven Impact of Monomeric Transthyretin on Amyloid-beta Amyloidogenesis

Yelim Yi, Bokyung Kim, Young Ho Ko, Jin Hae Kim, Mi Hee Lim

Version 1 posted 20 February 2024

258

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Organic Chemistry

Working Paper

Contilisant+Belinostat hybrids, as new multi-target-directed polyfunctionalized indole derivatives able to inhibit histone deacetylase/cholinesterase/monoamine oxidase enzymes, and modulate histamine 3/sigma 1/5-HT6/dopamine 3 receptors for the treatment of cancer and neurodegenerative diseases

Mireia Toledano-Pinedo, Alicia Porro, Saray Macaulet, Pedro Almendros, Isabel Iriepa, M. Mercedes Rodríguez-Fernández, Francisco López-Muñoz, Aizpea Artetxe-Zurutuza, Ander Matheu, José Marco-Contelles

Version 1 posted 03 August 2023

229

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Biological and Medicinal Chemistry

Working Paper

Successful Design of a Multivalent Bifunctional Chelator for Diagnostic 64Cu PET Imaging in Alzheimer’s Disease

Hong-Jun Cho, Truc T. Huynh, Buck E. Rogers, Liviu M. Mirica

Version 1 posted 05 June 2020

411

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Biological and Medicinal Chemistry

Working Paper

Amphiphilic Stilbene Derivatives Attenuate the Neurotoxicity of Soluble Aβ42 Oligomers by Controlling Their Interactions with Cell Membranes

Liviu M. Mirica

Version 2 posted 22 August 2022

405

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Biological and Medicinal Chemistry

Working Paper

Discovery of Potential GSK-3β Allosteric Modulators for Alzheimer’s Disease

Guilherme Martins Silva, Vinicius Medeiros Alves, Suzane Quintana Gomes, Joshua Earl Hochuli, Eugene Muratov, Alexander Tropsha, Carlos Henrique Tomich Paula Silva

Version 1 posted 23 March 2023

423

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1

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Biological and Medicinal Chemistry

Working Paper

Structural Impact of Pyroglutamylation at Glu3 in an Amyloid-β(3-42) Fibril Probed by Solid-State NMR Spectroscopy

Luis Gardon, Nina Becker, Lothar Gremer, Henrike Heise

Version 1 posted 08 June 2023

137

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Refine Search

21 results in Alzheimer’s disease in Keywords: Alzheimer’s disease

Amyloid Capture and Aggregation Inhibition by Human Serum Albumin

Amentoflavone: A Bifunctional Metal Chelator that Controls the Formation of Neurotoxic Soluble Aβ42 Oligomers

Amyloid Plaque Polymorphism is Associated with Distinct Lipid Accumulations Revealed by Trapped Ion Mobility Mass Spectrometry Imaging (TIMS MSI)

Contilistat, a new polyfunctionalized histone deacetylase inhibitor, showing potential capacity to inhibit cholinesterase/monoamine oxidase enzymes, and modulate histamine 3, sigma 1, 5-HT6 and dopamine 3 receptors for the treatment of cancer and neurodegenerative diseases

Zn(II)-Driven Impact of Monomeric Transthyretin on Amyloid-beta Amyloidogenesis

Contilisant+Belinostat hybrids, as new multi-target-directed polyfunctionalized indole derivatives able to inhibit histone deacetylase/cholinesterase/monoamine oxidase enzymes, and modulate histamine 3/sigma 1/5-HT6/dopamine 3 receptors for the treatment of cancer and neurodegenerative diseases

Successful Design of a Multivalent Bifunctional Chelator for Diagnostic 64Cu PET Imaging in Alzheimer’s Disease

Amphiphilic Stilbene Derivatives Attenuate the Neurotoxicity of Soluble Aβ42 Oligomers by Controlling Their Interactions with Cell Membranes

Discovery of Potential GSK-3β Allosteric Modulators for Alzheimer’s Disease

Structural Impact of Pyroglutamylation at Glu3 in an Amyloid-β(3-42) Fibril Probed by Solid-State NMR Spectroscopy

21 results in Keywords: Alzheimer’s disease