Search

Protein-Templated Hit Identification via an Ugi Four-Component Reaction

Federica Mancini, M. Yagiz Unver, Walid Elgaher, Varsha R. Jumde, Alaa Alhayek, Peer Lukat, jennifer herrmann, Martin D. Witte, Matthias Köck, Wulf Blankenfeldt, rolf müller, Anna K.H. Hirsch

Version 1 posted 31 January 2020

502

Downloads

Biological and Medicinal Chemistry

Working Paper

Biomimetic Enterobactin Analogue Mediates Iron-Uptake and Cargo Transport into E. coli and P. aeruginosa

Robert Zscherp, Janetta Coetzee, Johannes Vornweg, Jörg Grunenberg, jennifer herrmann, rolf müller, Philipp Klahn

Version 1 posted 17 December 2020

489

Downloads

Biological and Medicinal Chemistry

Working Paper

Targeting the energy-coupling factor (ECF) transporters: identification of new tool compounds

Eleonora Diamanti, Inda Setyawati, Spyridon Bousis, Paulo C. T. Souza, leticia mojas, lotteke Swier, Jörg Haupenthal, Paddy Gibson, carsten volz, weronika stanek, manuel Jaeger, jennifer herrmann, Siewert Marrink, jan-willem veening, rolf müller, dirk J. slotboom, Anna K.H. Hirsch

Version 2 posted 01 December 2021

1,181

Downloads

5

Citations

Organic Chemistry

Working Paper

Thiamyxins: Structure and Biosynthesis of Myxobacterial RNA-Virus-Inhibitors

Patrick Haack, Kirsten Harmrolfs, Chantal Bader, Ronald Garcia, Antonia Gunesch, Sibylle Haid, Alexander Popoff, Alexander Voltz, Heeyoung Kim, Ralf Bartenschlager, Thomas Pietschmann, Rolf Müller

Version 1 posted 01 September 2022

213

Downloads

Biological and Medicinal Chemistry

Working Paper

Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening

Di Zhu, Sandra Johannsen, Tiziana Masini, Céline Simonin, Jörg Haupenthal, Boris Illarionov, Anastasia Andreas, Mahendra Awale, Robin M. Gierse, Tridia van der Laan, Ramon van der Vlag, Rita Nasti, Mael Poizat, Eric Buhler, Norbert Reiling, Rolf Müller, Markus Fischer, Jean-Louis Reymond, Anna K. H. Hirsch

Version 2 posted 11 April 2022

373

Downloads

Organic Chemistry

Working Paper

Structure and Biosynthesis of Myxofacyclines: Unique Myxobacterial Polyketides Featuring Varying and Unprecedented Heterocycles

Alexander Popoff, Joachim Hug, Sebastian Walesch, Ronald Garcia, Lena Keller, Rolf Müller

Version 1 posted 19 July 2021

321

Downloads

Biological and Medicinal Chemistry

Working Paper

Inhibitors of the Elastase LasB for the treatment of Pseudomonas aeruginosa lung infections

Jelena Konstantinovic, Andreas M. Kany, Alaa Alhayek, Ahmed S. Abdelsamie, Asfandyar Sikandar, Katrin Voos, Yiwen Yao, Anastasia Andreas, Roya Shafiei, Brigitta Loretz, Esther Schönauer, Robert Bals, Hans Brandstetter, Rolf W. Hartmann, Christian Ducho, Claus-Michael Lehr, Christoph Beisswenger, Rolf Müller, Katharina Rox, Jörg Haupenthal, Anna Katharina Herta Hirsch

Version 1 posted 24 April 2023

382

Downloads

Organic Chemistry

Working Paper

Isolation of Fidaxomicin and Shunt Metabolites from Actinoplanes deccanensis

Erik Jung, Maja Hunter, Andrea Dorst, Alexander Major, Tatjana Teofilovic, Rolf Müller, Karl Gademann

Version 1 posted 25 January 2024

271

Downloads

Biological and Medicinal Chemistry

Working Paper

Activity and cryo-EM structure guided biosynthetic pathway engineering yields non-natural Darobactin antibiotics with superior activity against Gram-negative pathogens

Carsten E. Seyfert, Christoph Porten, Biao Yuan, Selina Deckarm, Fabian Panter, Chantal D. Bader, Janetta Coetzee, Felix Deschner, Kamaleddin H. M. E. Tehrani, Paul G. Higgins, Harald Seifert, Thomas Marlovits, Jennifer Herrmann, Rolf Müller

Version 2 posted 26 September 2022

828

Downloads

2

Citations

Biological and Medicinal Chemistry

Working Paper

Total In Vitro Biosynthesis of the Thioamitide Thioholgamide and Investigation of the Pathway

Asfandyar Sikandar, Maria Lopatniuk, Andriy Luzhetskyy, Rolf Müller, Jesko Koehnke

Version 1 posted 12 January 2022

499

Downloads

Refine Search

19 results in rolf müller in Authors: rolf müller

Protein-Templated Hit Identification via an Ugi Four-Component Reaction

Biomimetic Enterobactin Analogue Mediates Iron-Uptake and Cargo Transport into E. coli and P. aeruginosa

Targeting the energy-coupling factor (ECF) transporters: identification of new tool compounds

Thiamyxins: Structure and Biosynthesis of Myxobacterial RNA-Virus-Inhibitors

Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening

Structure and Biosynthesis of Myxofacyclines: Unique Myxobacterial Polyketides Featuring Varying and Unprecedented Heterocycles

Inhibitors of the Elastase LasB for the treatment of Pseudomonas aeruginosa lung infections

Isolation of Fidaxomicin and Shunt Metabolites from Actinoplanes deccanensis

Activity and cryo-EM structure guided biosynthetic pathway engineering yields non-natural Darobactin antibiotics with superior activity against Gram-negative pathogens

Total In Vitro Biosynthesis of the Thioamitide Thioholgamide and Investigation of the Pathway

19 results in Authors: rolf müller