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Rapid Hyperpolarization and Purification of the Metabolite Fumarate in Aqueous Solution

Stephan Knecht, John W. Blanchard, Danila Barskiy, Eleonora Cavallari, Laurynas Dagys, Erik van Dyke, Maksim Tsukanov, Bea Bliemel, Kerstin Münnemann, Silvio Aime, Francesca Reineri, Malcolm H. Levitt, Gerd Buntkowsky, Alexander Pines, Peter Blümler, Dmitry Budker, James Eills

Version 1 posted 03 September 2020

397

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1

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Biological and Medicinal Chemistry

Working Paper

In Vivo Molecular Imaging of Breast Cancer Metabolic Heterogeneity Using [1-13C]Pyruvate-d3 Hyperpolarized By Reversible Exchange With Parahydrogen

Stefan Petersen, Luca Nagel, Philipp Groß, Robert Willing, Lisa Heß, Julia Mitschke, Nicole Klemm, Judith Treiber, Christoph Müller, Stephan Knecht, Ilai Schwartz, Moritz Weigt, Michael Bock, Dominik von Elverfeldt, Maxim Zaitsev, Eduard Chekmenev, Jan-Bernd Hövener, Andre Martins, Franz Schilling, Thomas Reinheckel, Andreas Schmidt

Version 1 posted 01 August 2024

212

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Analytical Chemistry

Working Paper

In Vivo Metabolic Imaging of [1-13C]Pyruvate-d3 Hyperpolarized By Reversible Exchange With Parahydrogen

Henri de Maissin, Philipp Groß, Obaid Mohiuddin, Moritz Weigt, Luca Nagel, Marvin Herzog, Zirun Wang, Robert Willing, Wilfried Reichardt, Martin Pichotka, Lisa Heß, Thomas Reinheckel, Henning Jessen, Robert Zeiser, Michael Bock, Dominik von Elverfeldt, Maxim Zaitsev, Sergey Korchak, Stefan Glöggler, Jan-Bernd Hövener, Eduard Chekmenev, Franz Schilling, Stephan Knecht, Andreas Benjamin Schmidt

Version 1 posted 27 March 2023

675

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5

Citations

Physical Chemistry

Working Paper

Over 20% 13C Hyperpolarization for Pyruvate Using Deuteration and Rapid SLIC-SABRE in Mictrotesla Fields

Andreas B. Schmidt, James Eills, Laurynas Dagys, Martin Gierse, Michael Keim, Sebastian Lucas, Michael Bock, Ilai Schwartz, Maxim Zaitsev, Eduard Y. Chekmenev, Stephan Knecht

Version 1 posted 24 February 2023

552

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1

Citations

Analytical Chemistry

Working Paper

Hyperpolarizing Small Molecules using Parahydrogen-Induced Polarization and Solid-State Spin Diffusion

Martin Gierse, Laurynas Dagys, Michael Keim, Sebastian Lucas, Felix Josten, Martin B. Plenio, Ilai Schwartz, Stephan Knecht, James Eills

Version 1 posted 06 December 2023

240

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Physical Chemistry

Working Paper

Singlet to triplet conversion in molecular hydrogen and its role in parahydrogen induced polarization

Danil Markelov, Vitaly Kozinenko, Stephan Knecht, Alexey Kiryutin, Alexandra Yurkovskaya, Konstantin Ivanov

Version 1 posted 05 July 2021

225

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Organometallic Chemistry

Working Paper

Indirect Detection of Short-lived Hydride Intermediates of Iridium N-Heterocyclic Carbene Complexes via Chemical Exchange Saturation Transfer (CEST) Spectroscopy

Stephan Knecht,, Sara Hadjiali, Danila Barskiy, Alexander Pines, Grit Sauer, Alexey S Kiryutin, Konstantin Ivanov, Alexandra V. Yurkovskaya, Gerd Buntkowsky

Version 1 posted 24 April 2019

815

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Analytical Chemistry

Working Paper

Singlet-contrast magnetic resonance imaging: unlocking hyperpolarization with metabolism

James Eills, Eleonora Cavallari, Raphael Kircher, Ginevra Di Matteo, Carla Carrera, Laurynas Dagys, Malcolm H. Levitt, Konstantin Ivanov, Silvio Aime, Francesca Reineri, Kerstin Münnemann, Dmitry Budker, Gerd Buntkowsky, Stephan Knecht

Version 2 posted 10 September 2020

493

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Biological and Medicinal Chemistry

Working Paper

Parahydrogen-Polarized [1-13C]Pyruvate For Reliable and Fast Preclinical Metabolic Magnetic Resonance Imaging

Luca Nagel, Martin Gierse, Wolfgang Gottwald, Zumrud Ahmadova, Martin Grashei, Pascal Wolff, Felix Josten, Senay Karaali, Christoph A. Müller, Sebastian Lucas, Jochen Scheuer, Christoph Müller, John Blanchard, Geoffrey J. Topping, Andre Wendlinger, Nadine Setzer, Sandra Sühnel, Jonas Handwerker, Christophoros Vassiliou, Frits H. A. van Heijster, Stephan Knecht, Michael Keim, Franz Schilling, Ilai Schwartz

Version 1 posted 26 May 2023

471

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9 results in Stephan Knecht in Authors: Stephan Knecht

Rapid Hyperpolarization and Purification of the Metabolite Fumarate in Aqueous Solution

In Vivo Molecular Imaging of Breast Cancer Metabolic Heterogeneity Using [1-13C]Pyruvate-d3 Hyperpolarized By Reversible Exchange With Parahydrogen

In Vivo Metabolic Imaging of [1-13C]Pyruvate-d3 Hyperpolarized By Reversible Exchange With Parahydrogen

Over 20% 13C Hyperpolarization for Pyruvate Using Deuteration and Rapid SLIC-SABRE in Mictrotesla Fields

Hyperpolarizing Small Molecules using Parahydrogen-Induced Polarization and Solid-State Spin Diffusion

Singlet to triplet conversion in molecular hydrogen and its role in parahydrogen induced polarization

Indirect Detection of Short-lived Hydride Intermediates of Iridium N-Heterocyclic Carbene Complexes via Chemical Exchange Saturation Transfer (CEST) Spectroscopy

Singlet-contrast magnetic resonance imaging: unlocking hyperpolarization with metabolism

Parahydrogen-Polarized [1-13C]Pyruvate For Reliable and Fast Preclinical Metabolic Magnetic Resonance Imaging

9 results in Authors: Stephan Knecht