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Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway

Amy E. Fraley, Kersti Caddell Haatveit, Ying Ye, Samantha P. Kelly, Sean A. Newmister, Fengan Yu, Robert M. Williams, Janet L. Smith, K. N. Houk, David H. Sherman

Version 1 posted 21 August 2019

585

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Biological and Medicinal Chemistry

Working Paper

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity, Ligands for the CREBBP Bromodomain

Michael Brand, James Clayton, Mustafa Moroglu, Matthias Schiedel, Sarah Picaud, Joseph Bluck, Anna Skwarska, Anthony Chan, Corentine Laurin, Amy Scorah, Larissa See, Timothy Rooney, Oleg Fedorov, Gabriella Perell, Prakriti Kalra, Wilian Cortopassi, Kirsten Christensen, Richard Cooper, Robert Paton, William Pomerantz, Philip Biggin, Ester M. Hammond, Panagis Filippakopoulos, Stuart Conway

Version 1 posted 06 April 2020

625

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3

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Materials Chemistry

Working Paper

Errors in characterization and modeling undermine the report of the synthesis of γ-graphyne via alkyne metathesis

William Blake Martin, Robert Warburton, Shane M. Parker, Valentin Rodionov

Version 3 posted 18 July 2024

666

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Physical Chemistry

Working Paper

Room-Temperature Strong Coupling between CdSe Nanoplatelets and a Metal–DBR Fabry–Pérot Cavity

Ovishek Morshed, Mitesh Amin, Nicole M. B. Cogan, Eric R. Koessler, Robert Collison, Trevor M. Tumiel, William Girten, Farwa Awan, Lele Mathis, Pengfei Huo, A. Nickolas Vamivakas, Teri W. Odom, Todd D. Krauss

Version 3 posted 22 May 2024

905

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Organic Chemistry

Working Paper

Development of New Catalytic Asymmetric Routes towards a Cost-Driving Building Block of Nirmatrelvir

Robert Szpera, Shanjun Huang, Harriet A. M. Fenton, William Waddington, Adam E. S. Gymer, Ian Moses, Julia Buck, Heather Ingram, Steven J. Fussell, Robert Walton, Charles S. Shanahan, Sarah L. Aleshire, Juliana M. S. Robey, Hanuman P. Kalmode, Michel C. Nuckols, Nageswara R. Kalikinidi, Venumadhav Janganati, Sipak Joyasawal, Chanaka M. Amarasekarage, Chris Senanayake, B. Frank Gupton

Version 1 posted 31 January 2024

459

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1

Citations

Biological and Medicinal Chemistry

Working Paper

Control of Stereoselectivity in Diverse Hapalindole Metabolites Is Mediated by Cofactor Induced Combinatorial Pairing of Stig Cyclases

Shasha Li, Sean A. Newmister, andrew n. lowell, Jiachen Zi, Callie R. Chappell, Fengan Yu, Robert M. Hohlman, Jimmy Orjala, Robert M. Williams, David H. Sherman

Version 1 posted 25 October 2019

437

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Biological and Medicinal Chemistry

Working Paper

Flavin-Dependent Monooxygenases NotI and NotI′ Mediate Spiro-Oxindole Formation in Biosynthesis of the Notoamides

Amy E. Fraley, Hong T. Tran, Ashootosh Tripathi, Sean A. Newmister, Samantha P. Kelly, Hikaru Kato, Sachiko Tsukamoto, Shengying Li, Robert M. Williams, David H. Sherman

Version 1 posted 11 December 2019

552

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Biological and Medicinal Chemistry

Working Paper

Fungal Indole Alkaloid Biogenesis Through Evolution of a Bifunctional Reductase/Diels-Alderase

Qingyun Dan, Sean A. Newmister, Kimberly R. Klas, Amy E. Fraley, Timothy J. McAfoos, Amber D. Somoza, James D. Sunderhaus, Ying Ye, Vikram V. Shende, Fengan Yu, Jacob N. Sanders, W. Clay Brown, Le Zhao, Robert S. Paton, K. N. Houk, Janet L. Smith, David H. Sherman, Robert M. Williams

Version 1 posted 26 December 2018

1,275

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Physical Chemistry

Working Paper

Tracking Charge Transfer to Residual Metal Clusters in Conjugated Polymers for Photocatalytic Hydrogen Evolution

Michael Sachs, Hyojung Cha, Jan Kosco, Catherine M. Aitchison, Laia Francàs, Sacha Corby, Chao-Lung Chiang, Anna A. Wilson, Robert Godin, Alexander Fahey-Williams, Andrew I. Cooper, Seb Sprick, Iain McCulloch, James R Durrant

Version 1 posted 12 May 2020

1,167

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Biological and Medicinal Chemistry

Working Paper

Cofactor-Independent Pinacolase Directs Non-Diels-Alderase Biogenesis of the Brevianamides

Ying Ye, Lei Du, Xingwang Zhang, Sean A. Newmister, Wei Zhang, Shuai Mu, Atsushi Minami, Morgan McCauley, Juan V. Alegre-Requena, Amy E. Fraley, Maria L. Adrover-Castellano, Nolan Carney, Vikram V. Shende, Hideaki Oikawa, Hikaru Kato, Sachiko Tsukamoto, Robert S. Paton, Robert M. Williams, David H. Sherman, Shengying Li

Version 1 posted 29 July 2019

967

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1

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11 results in Robert M. Williams in Authors: Robert M. Williams

Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity, Ligands for the CREBBP Bromodomain

Errors in characterization and modeling undermine the report of the synthesis of γ-graphyne via alkyne metathesis

Room-Temperature Strong Coupling between CdSe Nanoplatelets and a Metal–DBR Fabry–Pérot Cavity

Development of New Catalytic Asymmetric Routes towards a Cost-Driving Building Block of Nirmatrelvir

Control of Stereoselectivity in Diverse Hapalindole Metabolites Is Mediated by Cofactor Induced Combinatorial Pairing of Stig Cyclases

Flavin-Dependent Monooxygenases NotI and NotI′ Mediate Spiro-Oxindole Formation in Biosynthesis of the Notoamides

Fungal Indole Alkaloid Biogenesis Through Evolution of a Bifunctional Reductase/Diels-Alderase

Tracking Charge Transfer to Residual Metal Clusters in Conjugated Polymers for Photocatalytic Hydrogen Evolution

Cofactor-Independent Pinacolase Directs Non-Diels-Alderase Biogenesis of the Brevianamides

11 results in Authors: Robert M. Williams