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    • Radosław P. Nowak

    3 results in Authors: Radosław P. Nowak

    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    Development and characterization of the first selective class IIb histone deacetylase degraders

    , Authors: Shiyang Zhai, Irina Honin, Linda Schäker-Hübner, Maria Hanl, Lukas Jacobi, Finn Dressler, Dominika Ewa Pieńkowska, Philipp König, Jan Gerhartz, Rabea Voget, Gerd Bendas, Michael Gütschow, Felix Meissner, Björn Burckhardt, Radosław P. Nowak, Christian Steinebach, Finn Kristian Hansen
    Version 3 posted 06 March 2025
    618
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    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    Breaking Barriers in PROTAC Design: Improving Solubility of USP7-Targeting Degraders

    , Authors: Sophie Wittenburg, Maximilian R. Zuleeg, Kirsten Peter, Patricia Lemnitzer, Rabea Voget, Aleša Bricelj, Martina Gobec, Nele Dierlamm, Michael B. Braun, Thomas M. Geiger, Christopher Heim, Alicia Stakemeier, Karl G. Wagner, Radosław P. Nowak, Marcus D. Hartmann, Izidor Sosič, Michael Gütschow, Jan Krönke, Christian Steinebach
    Version 1 posted 03 March 2025
    238
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    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    Discovery of histone deacetylase 8 (HDAC8)-specific proteolysis-targeting chimeras with anti-cancer activity against hematological malignancies

    , Authors: Shiyang Zhai, Marie Kemkes, Cindy-Esther Kponomaizoun, Felix Feller, Jia-Wey Tu, Dominika Ewa Pieńkowska, Jan Gerhartz, Julian Schliehe-Diecks, Michael Gütschow, Radosław P. Nowak, Christian Steinebach, Sanil Bhatia, Finn Kristian Hansen
    Version 1 posted 04 April 2025
    0
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