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6 results in Authors: Jacob A. Larsen

Biological and Medicinal Chemistry

Exploring the NCS-382 Scaffold for CaMKIIα Modulation: Synthesis, Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant Stabilizer of the CaMKIIα Hub Domain

Yongsong Tian, Mohamed Shehata, Stine Gauger, Carolina Veronesi, Louise Hamborg, Louise Thiesen, Jesper Bruus-Jensen, Johanne Schlieper Royssen, Ulrike Leurs, Anne Sofie Larsen, Jacob Krall, Sara Solbak, Petrine Wellendorph, Bente Frølund

Version 1 posted 30 May 2022

298

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Analytical Chemistry

Thermodynamic characterization of amyloid polymorphism by Taylor dispersion analysis

Azad Farzadfard, Antonin Kunka, Thomas O. Mason, Jacob A. Larsen, Rasmus K. Norrild, Elisa Torrescasana Dominguez, Soumik Ray, Alexander K. Buell

Version 1 posted 05 October 2023

479

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Analytical Chemistry

Capillary Flow Experiments (Capflex) for Thermodynamic and Kinetic Characterization of Protein LLPS at High Throughput

Emil G. P. Stender, Rasmus Krogh Norrild, Jacob Aunstrup Larsen, Henrik Jensen, Alexander Buell

Version 1 posted 23 March 2021

657

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Organic Chemistry

Diversity in a Bottle: Iminium Ions as a Platform for N-(Hetero)Aryl Piperidine Synthesis

Jacob Greenwood, Matthew Larsen, Samantha Burgess, Justin Newman, Yuan Jiang, Aaron C. Sather

Version 1 posted 20 May 2022

993

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Physical Chemistry

The mechanism of amyloid fibril growth from Φ-value analysis

Jacob Aunstrup Larsen, Abigail Barclay, Nicola Vettore, Louise K. Klausen, Lena Mangels, Alberto Coden, Jeremy Schmit, Kresten Lindorff-Larsen, Alexander K. Buell

Version 1 posted 19 February 2024

727

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Biological and Medicinal Chemistry

Probing the effect of the disordered flank regions on amyloid fibril growth and proliferation

Jacob Aunstrup Larsen, Juami van Gils, Soumik Ray, Marcel Dickmanns, Hossein Mohammad-Beigi, Masoumeh Zanganeh, Sanne Abeln, Alexander Kai Buell

Version 1 posted 30 October 2024

571

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