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    • Aleša Bricelj

    5 results in Authors: Aleša Bricelj

    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs

    , Authors: Christian Steinebach, Izidor Sosič, Aleša Bricelj, Arunima Murgai, Luca Bischof, Yuen Lam Dora Ng, Christopher Heim, Samuel Maiwald, Matic Proj, Rabea Voget, Felix Feller, Janez Košmrlj, Annika Schmidt, Patricia Lemnitzer, Finn K. Hansen, Michael Gütschow, Jan Krönke, Marcus D. Hartmann
    Version 1 posted 21 April 2023
    1,762
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    1
    Citations
    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    Breaking Barriers in PROTAC Design: Improving Solubility of USP7-Targeting Degraders

    , Authors: Sophie Wittenburg, Maximilian R. Zuleeg, Kirsten Peter, Patricia Lemnitzer, Rabea Voget, Aleša Bricelj, Martina Gobec, Nele Dierlamm, Michael B. Braun, Thomas M. Geiger, Christopher Heim, Alicia Stakemeier, Karl G. Wagner, Radosław P. Nowak, Marcus D. Hartmann, Izidor Sosič, Michael Gütschow, Jan Krönke, Christian Steinebach
    Version 1 posted 03 March 2025
    238
    Downloads
    Category: Biological and Medicinal Chemistry
    ,
    Working Paper
    , Title:

    Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1alpha (HIF-1alpha) Stabilizers

    , Authors: Lan Phuong Vu, Claudia Diehl, Ryan Casement, Adam Bond, Christian Steinebach, Nika Strasek, Alesa Bricelj, Andrej Perdih, Gregor Schnakenburg, Izidor Sosic, Alessio Ciulli, Michael Gutschow
    Version 2 posted 01 August 2023
    1,309
    Downloads