Design of a Gas Rapid Injection NMR System for Structure Elucidations and Kinetic Analyses

A gas rapid injection nuclear magnetic resonance (GRI-NMR) system has been constructed to investigate reactions requiring the use of gas reagents. The system allows for the accurate delivery of gases under inert conditions to a standard NMR glass tube inside the spectrometer permitting in situ reaction monitoring to be conducted which mimics reactions performed at the bench. The system provides a unique avenue to investigate reaction systems that require a continuous and/or precise delivery of gas reagents. To showcase our newly constructed GRI-NMR system, the reaction of carbon dioxide binding with phosphine ligated nickel zero complexes were monitored in real time providing detailed kinetic data.