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Abstract
Exploring the chemical space of prebiotic reactions is crucial for understanding the emergence of
life. However, the combinatorial explosion of compounds and the lack of user-friendly computational
tools pose significant challenges. To address these issues, we developed Rule-it, a web platform that
enables prebiotic chemists to build, expand, prune, and visualize chemical reaction networks. The
platform integrates experimental data and provides a comprehensive framework for studying chemical
evolution. By simplifying the generation and analysis of reaction networks, Rule-it aims to advance
research in prebiotic chemistry.
Supplementary materials
Title
Supplementary materials
Description
Supplementary tables with lists of reaction rules and compounds.
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