Gabriel Synthesis of Aminomethyl-Bicyclo[1.1.0]butanes

08 August 2024, Version 1

Abstract

The reaction of iodo-bicyclo[1.1.1]pentanes with potassium phthalimide yields phthalimide-substituted bicyclo[1.1.0]butanes (BCBs), which upon hydrazinolysis afford the corresponding aminomethyl-BCB products.

Keywords

BCP
BCB
Bicyclobutanes
Bicyclo[1.1.0]butanes
Bicyclo[1.1.1]pentanes

Supplementary materials

Title
Description
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Title
Electronic Supporting Information
Description
Procedures, NMR spectra, X-ray structures
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