Abstract
In recent years, ultrasound-mediated drug delivery systems have emerged as a non-invasive technology for pharmaceutical and tissue engineering applications. One of the significant disadvantages of transdermal drug delivery systems is the limited permeation of drugs through the stratum corneum layer of the human skin. Using ultrasound on the skin surface enhances the skin's permeability, improving drug delivery efficiency. This review highlights the role of ultrasound in enhancing the efficiency of current drug delivery systems. It also discusses the role of ultrasound in guiding the fabrication of artificial tissues, delivery of signaling molecules, and imaging technology for tissue engineering applications.