Straightforward Synthesis of Molsidomine and Mesocarb Analogue via Mechanochemical Desymmetrization of CDI

29 November 2023, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

The mechanosynthesis of N6-functionalized iminosydnones was performed via a convergent strategy based on the desymmetrization of CDI. The whole process was carried out by ball-milling, offering an efficient and sustainable access to bioactive iminosydnones.

Keywords

Mechanochemistry
Ball-mill
Sydnone
Heterocycles
Green chemistry
sustainable synthesis

Supplementary materials

Title
Description
Actions
Title
Straightforward Synthesis of Molsidomine and Mesocarb Analogue via Mechanochemical Desymmetrization of CDI
Description
Optimization of reaction conditions, experimental procedures and analytical data, NMR spectra
Actions

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