Simulation using Newton-Raphson Method for a Hypothetical Divalent Complex with a Vertical Plane of Symmetry

We briefly formulate a derivation of the multivalent equilibrium model to give an alternative option. This would take a minor assumption given a hypothetical host-guest complex with a vertical plane of symmetry. From these works, we carefully take a look at three cases of cooperativity factors given three different concentrations. Also, we considered an intuition for Job plots frequently used in supramolecular host-guest chemistry. All simulations using Newton-Raphson method were conducted in simple Python codes.