Abstract
In recent days, increasing number of microbes and their increasing resistance power against conventional drugs lead to enormous worldwide mortalities, hence they become a great threat to human health. The modern era is already going through the threat of COVID 19, which is also caused by one of those microbes called virus. In order to get a clear understanding, all the microbes have been classified in certain types. Now a days, to develop new alternative antimicrobial medicines, the scientists must acquire clarity about the responsible functional groups of different conventional drugs with proper mechanistic elucidation on different types of microbes. This information not only clarify the functionalities and properties responsible to exhibit antimicrobial effects, but also facile the idea of new drug development in future through proper functional group incorporation or modification. In this essay, my focus will majorly be on the main four types of microbes and their possible mechanistic elucidation of commonly used antibiotics and alternative antimicrobial medicines discovered till now.