Tantalum Ureate Complexes for Photocatalytic Hydroaminoalkylation

Using a tantulum ureate pre-catalyst, photocatalytic hydroaminoalkylation of unactivated alkene with unprotected amine at room temperature is demonstrated. The conbination of Ta(CH2SiMe3)3Cl2 and ureate ligand with saturated cyclic backbone resulted in unique reactivity. The substrate scope of Ta photocatalytic hydroaminoalkylation (β-alkylation of amine) was evaluated. Preliminary investigation on reaction mechanism suggests both similarities and differences with Ta catalyzed hydroaminoalkyaltion under thermo conditions