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On the reactions of aryl and vinyl triflates with [Ni(COD)(dppf)]

26 May 2022, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

We report the experimental and computational investigations of the reactions of aryl and vinyl triflates with a model nickel(0) complex. Oxidative addition rates decrease in the order naphthyl > vinyl > phenyl, although 4-acetylphenyl triflate reacts most quickly due to favourable ketone coordination. Two possible reaction mechanisms are explored using DFT calculations.

Keywords

nickel catalysis
cross-coupling
oxidative addition

Supplementary materials

Title
Description
Actions
Title
Kinetic Data
Description
Kinetic Data
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Supporting Information
Description
Supporting Information
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DFT Coordinates
Description
DFT Coordinates
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Version History

May 26, 2022 Version 1

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License

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CC
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BY
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NC
The content is available under CC BY NC 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2022-g8ng1
D O I: 10.26434/chemrxiv-2022-g8ng1 [opens in a new tab]

Funding

AstraZeneca
Engineering and Physical Sciences Research Council
EP/R512114/1

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

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