A photo-responsive modulation of trans-zeatin

Liang Cheng; Xin Sun; Li Liu

doi:10.26434/chemrxiv-2022-d5x5j

Biological and Medicinal Chemistry

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A photo-responsive modulation of trans-zeatin

13 January 2022, Version 1

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Abstract

Photo-irradiation of an appropriately designed caged hormones enables the control and manipulation of the corresponding biological processes with high spatial and temporal resolution. Caged trans-zeatin of various types of nitrobenzene carbonate related photoremovable protecting groups have been synthesized. A rapid irradiation liberates the trapped trans-zeatin molecule, permitting targeted perturbation of biological processes including degradation, glucosylation and recognition by appropriate enzymes.

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