Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Reactivity-Selectivity Principle: Phenyl Group in Indazole Makes It More Lucid

15 December 2021, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Linear free energy relationship (LFER) plots are constructed for the deprotonation equilibriums (pKaH+) of pyrazolium and indazolium (benzopyrazolium) cations. The reaction constants Taft * and Hammett  are found to be 2.75 and 1.32 for deprotonation (pKaH+) of pyrazolium and indazolium cations respectively. Higher value of Taft * than the Hammett  is explained in terms of extra stability of the indazolium cation due to its greater number of resonance structures. This article is an exercise to undergraduate students for writing different resonance structures of indazolium cation.

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Version History

Dec 15, 2021 Version 1

Metrics

491
138
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
The content is available under CC BY 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2021-9jdkr
D O I: 10.26434/chemrxiv-2021-9jdkr [opens in a new tab]

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

Share