Phosphonic acid appended naphthalenediimide molecular receptor for saccharides and aminoglycoside antibiotics recognition

25 October 2021, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Design of symmetric phosphonic acid functionalized naphthalene diimide bolaamphiphile (NDI 1) is reported. NDI 1 based molecular recognition of saccharides and aminoglycoside antibiotics in aqueous media was investigated. UV-vis and fluorescence measurements revealed an efficient protocol for NDI 1 as molecular receptor. The sensor successfully recognises saccharides and aminoglycoside antibiotics kanamycin and neomycin in terms of both absorbance intensity and binding affinity. This protocol provides new platform for the design and synthesis of phosphonic acid appended NDI sensor for recognition of multifunctional biomolecules.

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