![Author ORCID: We display the ORCID iD icon alongside authors names on our website to acknowledge that the ORCiD has been authenticated when entered by the user. To view the users ORCiD record click the icon. [opens in a new tab]](https://chemrxiv.org/engage/assets/public/chemrxiv/images/logos/orcid.png)
Abstract
A first report on transition-metal-free aluminium chloride mediated isocyanide insertion between two amine nucleophiles have been presented. Also, an unusual C-N bond cleavage allow for the further development of copper mediated ring open-ing cyclization (SROC) strategy for the synthesis of azole fused benzimidazoquinazoline scaffolds. The key features of this protocol are aluminium chloride as non-transition-metal based mediator, oxidant/base/ligand free isocyanide insertion, three new C-N and one C-C bond formations and simultaneous construction of multiprivileged azole fused benzimidazoquinazo-line in good yields.
Supplementary materials
Title
Aluminium Mediated Isocyanide Insertion and Sequential Ring Opening Cyclization (SROC) Strategy: Synthesis of Azole Fused Benzimidazoquinazoline Skeletons
Description
Supporting information
Actions
Title
Graphical abstract
Description
A first report on transition-metal-free aluminium chloride mediated isocyanide insertion between two amine nucleophiles have been presented. Also, an unusual C-N bond cleavage allow for the further development of copper mediated ring open-ing cyclization (SROC) strategy for the synthesis of azole fused benzimidazoquinazoline scaffolds. The key features of this protocol are aluminium chloride as non-transition-metal based mediator, oxidant/base/ligand free isocyanide insertion, three new C-N and one C-C bond formations and simultaneous construction of multiprivileged azole fused benzimidazoquinazo-line in good yields.
Actions
Title
cif file
Description
X-ray data
Actions
Title
Covering letter
Description
Covering letter
Actions
Supplementary weblinks
Title
website address of corresponding author
Description
website address of corresponding author
Actions
View 
