Palladium-Catalyzed intramolecular Cyclization of ‘2-bromo-1,5-
di-ene-7-yne’System: A Versatile Route to the Poly-ene
Substituted Cyclohexenols

Jayanta Kumar Ray; Sunanda Paul; Raju Singha

doi:10.26434/chemrxiv-2021-5cqps

Materials Science

Search within Materials Science

Palladium-Catalyzed intramolecular Cyclization of ‘2-bromo-1,5- di-ene-7-yne’System: A Versatile Route to the Poly-ene Substituted Cyclohexenols

22 June 2021, Version 1

Working Paper

Show author details

This content is a preprint and has not undergone peer review at the time of posting.

Abstract

A general and efficient methodology has been developed for the synthesis of substituted cyclohexenol system with conjugated bis-exocyclic diene via Pd-catalyzed intramolecular 6-exo-dig cyclization of ‘ene-yne’ moiety. This method is straight forward and high yielding.

Keywords

Pd catalyzed reactions

organometallic

Coupling reaction

organic synthesis

Substituted Cyclohexenols

intramolecular Cyclization

poly-ene

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here .

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Version History

Jun 22, 2021 Version 1

Metrics

664

236

Views

Downloads

Citations

License

The content is available under CC BY NC ND 4.0

DOI

10.26434/chemrxiv-2021-5cqps

Funding

DST

CSIR-Central Scientific Instruments Organisation

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content