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Preparation of 2-((4-Methylpentan-2-Yl)amino)-5-(Phenylamino)cyclohexa-2,5-Diene-1,4-Dione (6PPD-Quinone), an Environmental Hazard for Salmon

04 February 2021, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

A recent report has identified 6PPD-quinone as an environmental compound responsible for drastic declines in coho salmon (Oncorhynchus kisutch) populations. As it is derived by oxidation of the preservative 6PPD that is found in tire rubber, this compound is not commercially available for further investigation of its biological properties. This work provides a brief synthesis of the oncorhynchicide 6PPD-quinone that can be used for that purpose.

Keywords

tire antioxidant
environmental toxicology

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Version History

Feb 04, 2021 Version 1

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The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.13698985.v1
D O I: 10.26434/chemrxiv.13698985.v1 [opens in a new tab]

Author’s competing interest statement

No conflicts to declare.

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