Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Collaborative Virtual Screening to Elaborate an Imidazo[1,2-A]pyridine Hit Series for Visceral Leishmaniasis

04 November 2020, Version 1

Abstract

An innovative pre-competitive virtual screening collaboration was engaged to validate and subsequently explore an imidazo[1,2-a]pyridine screening hit for visceral leishmaniasis. Parasitology and early ADME data is presented.

Keywords

Infectious Disease
Medicinal Chemistry
In silico
Leishmania donovani
leishmaniasis treatment
Collaboration Networks Community structures

Supplementary materials

Title
Description
Actions
Title
SI 1 intro and assays final
Description
Actions
Title
SI 2 - Table of compounds final
Description
Actions
Title
SI 3 - experimental final
Description
Actions
Title
SI 4 - Analytical data final
Description
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Version History

Nov 04, 2020 Version 1

Version Notes

v1 - submitted for peer review

Metrics

1,650
401
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
NC logo
NC
ND logo
ND
The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.13134785.v1
D O I: 10.26434/chemrxiv.13134785.v1 [opens in a new tab]

Funding

GHIT

Author’s competing interest statement

There are no conflicts of interest to declare

Share