A Single-Step Synthesis of 1,3,4,6-Tetraaryl-5-Aryliminopiperazin-2-One

27 May 2020, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

We report here novel reaction that we found unprecedented, up to our knowledge. In a single step, we obtained unusual result. After magnificent efforts we could deduce the structure. We confirmed the structure of this product by reproducing the reaction using other substrates. The reaction therefore resulted in a piperazine ring that is functionalized on every atom in the ring. This was stage 1. We almost finished making this reaction more utilizable (stage 2) in a future paper. Enjoy it because you won't see a new chemistry everyday.

Keywords

Piperazine
Lewis acid catalysis
Glyoxal
cyclization chemistry
highly substituted piperzine
piperazinone ring
Cerium Ammonium Nitrate
Montmorillonite
arylamine derivatives

Supplementary materials

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Piperazinone 2020525
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