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Palladium–Catalysed Magnesiation of Benzene

14 September 2018, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

In the presence of a catalytic quantity of a palladium bis(phosphine) complex, a reagent containing a Mg-Mg bond effects the C-H functionalisation of benzene. The resulting 100% atom efficient transformation generates an unprecedented aryl magnesium hydride.

Keywords

C–H activation
Grignard compound
Palladium Catalysis
C–H Magnesiation

Supplementary materials

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SI CH-Magnesiation 30thJuly
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Now Published

Palladium-catalysed magnesiation of benzene [opens in a new tab]
Martí Garçon, Andrew J. P. White, Mark R. Crimmin journal article
Chemical Communications , Volume 54, Issue 87
Online publication date: 2018

Version History

Sep 14, 2018 Version 1

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The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.7082987.v1
D O I: 10.26434/chemrxiv.7082987.v1 [opens in a new tab]

Funding

We are grateful to the European Research Council (FluoroFix:677367) and the Royal Society (UF090149). Johnson Matthey are thanked for generous donation of PdCl2.

Author’s competing interest statement

The authors declare no conflict of interest.

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