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Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides

13 August 2018, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Highly enantioselective Hiyama cross-coupling reactions have been achieved through rhodium(I)-catalyzed dynamic kinetic asymmetric transformations between aryl siloxanes and racemic allyl halides. This process affords valuable enantiomerically enriched allyl arenes and is compatible with heterocyclic allyl chloride electrophiles.

Keywords

Hiyama Coupling
DYKAT
Allylation

Supplementary materials

Title
Description
Actions
Title
Supporting Information - Rh Hiyama Allyl
Description
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Now Published

Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides [opens in a new tab]
Jesús González, Philipp Schäfer, Stephen P. Fletcher journal article
Organometallics , Volume 38, Issue 20
Online publication date: May 10, 2019

Version History

Aug 13, 2018 Version 1

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The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.6960404.v1
D O I: 10.26434/chemrxiv.6960404.v1 [opens in a new tab]

Funding

Engineering and Physical Sciences Research Council (EP/N022246/1), Marie Skłodowska-Curie fellowship (GA 700108)

Author’s competing interest statement

No conflict of interest

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