Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Small-Molecule (Micro)arrays for Sensitive Multiplex Metabolites Detection by Surface Plasmon Resonance Imaging

01 March 2018, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Small-molecule (micro)arrays were developed to measure three metabolites simultaneously by surface plasmon resonance imaging for the first time. To tackle the low sensitivity challenge associated with small molecule detection, antibodies were employed as the signal amplifiers. This work demonstrates both inhibition and displacement formats are applicable for sensitive multiplex metabolites detection.

Keywords

surface plasmon resonance imaging
multiplex assay
small-molecule metabolites
small-molecule microarrays

Supplementary materials

Title
Description
Actions
Title
AC4 ESI ChemRxiv
Description
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Version History

Mar 01, 2018 Version 1

Metrics

2,758
505
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
NC logo
NC
ND logo
ND
The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.5930644.v1
D O I: 10.26434/chemrxiv.5930644.v1 [opens in a new tab]

Funding

Alberta Innovate Health Solutions and Natural Sciences and Engineering Research Council of Canada

Author’s competing interest statement

No conflict of interest.

Share